Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 3/20 | 0.54 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.54 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.54 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.54 |
| ▸ | LSS | P48449 | 3/20 | 0.54 |
| ▸ | DRD2 | P14416 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.49 |
| ▸ | HRH1 | P35367 | 2/20 | 0.49 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.48 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.48 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2077734 | 1.00 | KCNH2 (0.54) | KCNH2SLC6A2SLC6A4SLC6A3LSS | |
| SCHEMBL24394470 | 1.00 | KCNH2 (0.54) | KCNH2SLC6A2SLC6A4SLC6A3LSS | |
| SCHEMBL10079167 | 0.95 | KCNH2 (0.60) | KCNH2SLC6A2SLC6A4SLC6A3LSS | |
| SCHEMBL13416053 | 0.89 | NPC1 (0.47) | KCNH2SLC6A2SLC6A4SLC6A3LSS | |
| SCHEMBL2606075 | 0.89 | NPC1 (0.47) | KCNH2SLC6A2SLC6A4SLC6A3LSS | |
| SCHEMBL19993071 | 0.86 | APOBEC3A (0.48) | KCNH2SLC6A2SLC6A4SLC6A3LSS | |
| SCHEMBL13015008 | 0.86 | QDPR (0.49) | KCNH2LSSCYP2D6CHRM1HRH1 | |
| SCHEMBL12950820 | 0.84 | SLC6A2 (0.55) | KCNH2SLC6A2SLC6A4SLC6A3LSS | |
| SCHEMBL23469162 | 0.84 | SLC6A2 (0.55) | KCNH2SLC6A2SLC6A4SLC6A3LSS | |
| SCHEMBL24310166 | 0.82 | SLC6A2 (0.54) | KCNH2SLC6A2SLC6A4SLC6A3LSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090711-A1 | COMPOUNDS AS CD73 INHIBITORS | AdoRx Therapeutics Limited (GB) | 2022-05-05 | — | — | WO | disclosed |