⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5432231 | 1.00 | — | — | |
| SCHEMBL972246 | 1.00 | — | — | |
| SCHEMBL2488591 | 1.00 | — | — | |
| SCHEMBL70413 | 1.00 | — | — | |
| SCHEMBL9740958 | 0.78 | — | — | |
| SCHEMBL11879180 | 0.76 | — | — | |
| SCHEMBL596776 | 0.68 | — | — | |
| SCHEMBL3130602 | 0.67 | — | — | |
| SCHEMBL2449018 | 0.65 | CHRM2 (0.37) | — | |
| SCHEMBL9343558 | 0.65 | CHRM2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 32 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20130040934-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIVERSITY OF BASEL (CH) | 2013-02-14 | — | — | US | claimed |
| EP-0532178-B1 | Methanoanthracenes as dopamine antagonists | ZENECA LTD (GB) | 1996-10-16 | — | — | EP | claimed |
| US-5455246-A | Treating neuropsychiatric disorders | IMPERIAL CHEMICAL INDUSTRIES, PLC (GB) | 1995-10-03 | — | — | US | claimed |
| EP-0532178-A1 | Methanoanthracenes as dopamine antagonists | ZENECA LIMITED (GB) | 1993-03-17 | — | — | EP | claimed |
| US-5104872-A | Agricultural or horticultural fungicides | NIHON HOHYAKU CO., LTD. (JP) | 1992-04-14 | — | — | US | claimed |
| US-4398940-A | PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1983-08-16 | — | — | US | claimed |
| US-4323677-A | LEGUME PLANT GROWTH REGULATOR | MONSANTO COMPANY (US) | 1982-04-06 | — | — | US | claimed |
| EP-0003075-A1 | N-Amides of 2-benzothiazolinone and their use as plant growth regulants | MONSANTO COMPANY (US) | 1979-07-25 | — | — | EP | claimed |
| US-20230192704-A1 | MONOCARBOXYLIC ACID TRANSPORTER 4 (MCT4) MODULATORS AND USES THEREOF | TEON THERAPEUTICS INC (US) | 2023-06-22 | — | — | US | disclosed |
| US-20130040934-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIVERSITY OF BASEL (CH) | 2013-02-14 | — | — | US | disclosed |
| EP-2547684-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | University of Basel (CH) | 2013-01-23 | — | — | EP | disclosed |
| WO-2011114275-A1 | SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES | UNIVERSITY OF BASEL (CH) | 2011-09-22 | — | — | WO | disclosed |
| US-20070167631-A1 | Novel herbicides | Luthy, Christoph (CH) | 2007-07-19 | — | — | US | disclosed |
| EP-1692108-A1 | NOVEL HERBICIDES | Syngenta Participations AG (CH) | 2006-08-23 | — | — | EP | disclosed |
| EP-0362645-A2 | Use of pteridines in the prevention of the primary and secondary resistance during chemotherapy, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1990-04-11 | — | — | EP | disclosed |
| WO-1990002122-A1 | FUNGICIDAL BENZODIOXANE AMINE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1990-03-08 | — | — | WO | disclosed |
| US-4398940-A | PLANT GROWTH REGULATORS | MONSANTO COMPANY (US) | 1983-08-16 | — | — | US | disclosed |
| US-4323677-A | LEGUME PLANT GROWTH REGULATOR | MONSANTO COMPANY (US) | 1982-04-06 | — | — | US | disclosed |
| EP-0003075-A1 | N-Amides of 2-benzothiazolinone and their use as plant growth regulants | MONSANTO COMPANY (US) | 1979-07-25 | — | — | EP | disclosed |
| EP-0003075-A1 | N-Amides of 2-benzothiazolinone and their use as plant growth regulants | MONSANTO COMPANY (US) | 1979-07-25 | — | — | EP | disclosed |