Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9343558 | 1.00 | CHRM2 (0.37) | CHRM2CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL9340709 | 1.00 | CHRM2 (0.37) | CHRM2CHRM3CHRM4CHRM5CHRM1 | |
| SCHEMBL9740958 | 0.87 | — | — | |
| SCHEMBL7153979 | 0.74 | — | — | |
| SCHEMBL9214995 | 0.72 | — | — | |
| SCHEMBL872855 | 0.71 | — | — | |
| SCHEMBL12657856 | 0.71 | — | — | |
| SCHEMBL232761 | 0.69 | — | — | |
| SCHEMBL8751150 | 0.69 | — | — | |
| SCHEMBL8751032 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8575153-B2 | Pyridine-3-carboxyamide derivative | KOWA COMPANY, LTD. (JP) | 2013-11-05 | — | — | US | disclosed |
| EP-2492265-A1 | 1,2,4-Thiadiazole Compounds and Pests Controlling Composition Containing the same | Sumitomo Chemical Company, Limited (JP) | 2012-08-29 | — | — | EP | disclosed |
| EP-2380877-A1 | PYRIDINE-3-CARBOXYAMIDE DERIVATIVE | Kowa Company, Ltd. (JP) | 2011-10-26 | — | — | EP | disclosed |
| US-20110237590-A1 | PYRIDINE-3-CARBOXYAMIDE DERIVATIVE | KOWA COMPANY, LTD. (JP) | 2011-09-29 | — | — | US | disclosed |
| CN-101208318-B | 1,2, 4-thiadiazole compound and pest control composition comprising the same | SUMITOMO CHEMICAL CO | 2010-11-03 | — | — | CN | disclosed |
| CN-101208318-A | 1,2, 4-thiadiazole compound and pest control composition comprising the same | SUMITOMO CHEMICAL CO (JP) | 2008-06-25 | — | — | CN | disclosed |
| US-7371746-B2 | 1,2,4-Thiadiazole compounds and pests controlling composition containing the same | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 2008-05-13 | — | — | US | disclosed |
| EP-1765798-A2 | 1,2,4- THIADIAZOLE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | Sumitomo Chemical Company, Limited (JP) | 2007-03-28 | — | — | EP | disclosed |
| US-20070004722-A1 | 1,2,4-Thiadazole compounds and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-01-04 | — | — | US | disclosed |
| WO-2005037805-A2 | 1,2,4-THIADIAZOLE COMPOUNDS AND PESTS CONTROLLING COMPOSITION CONTAINING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-04-28 | — | — | WO | disclosed |
| EP-0362645-B1 | Use of pteridines in the prevention of the primary and secondary resistance during chemotherapy, and medicaments containing these compounds | THOMAE GMBH DR K (DE) | 1994-06-08 | — | — | EP | disclosed |
| EP-0362645-A2 | Use of pteridines in the prevention of the primary and secondary resistance during chemotherapy, and medicaments containing these compounds | Dr. Karl Thomae GmbH (DE) | 1990-04-11 | — | — | EP | disclosed |
| EP-0006992-A1 | 3-(p-Isopropyl-phenyl)-2-methyl-n-propyl amines, fungicides containing these compounds, a method for the preparation of said compounds and a method for combating fungi by using said compounds | BASF Aktiengesellschaft (DE) | 1980-01-23 | — | — | EP | disclosed |
| US-4070461-A | ANTICHOLESTEROL | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DT) | 1978-01-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070004722-A1 | 1,2,4-Thiadazole compounds and use thereof | CYP4F3, CYP4B1, CYP4X1 | CHRM2 348/4885CHRM3 356/4885CHRM4 290/4885 |
| US-20110237590-A1 | PYRIDINE-3-CARBOXYAMIDE DERIVATIVE | JAK3, JAK1, UACA | CHRM2 2286/4885CHRM3 667/4885CHRM4 2585/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.