Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CECR2 | Q9BXF3 | 3/20 | 0.48 |
| ▸ | BRD4 | O60885 | 15/20 | 0.47 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.46 |
| ▸ | TAF1 | P21675 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397895 | 0.90 | BRD4 (0.47) | CECR2BRD4BRD9 | |
| SCHEMBL24397906 | 0.89 | BRD4 (0.49) | BRD4 | |
| SCHEMBL24398081 | 0.87 | BRD4 (0.46) | BRD4 | |
| SCHEMBL24397954 | 0.87 | BRD4 (0.46) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL24398000 | 0.87 | BRD4 (0.46) | BRD4 | |
| SCHEMBL24398044 | 0.86 | BRD4 (0.55) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL24397990 | 0.85 | BRD4 (0.46) | BRD4 | |
| SCHEMBL24398005 | 0.85 | BRD9 (0.47) | CECR2BRD4BRD9TAF1 | |
| SCHEMBL24398083 | 0.84 | BRD4 (0.57) | BRD4TAF1 | |
| SCHEMBL24397885 | 0.84 | BRD4 (0.48) | CECR2BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090699-A1 | PYRIDONE-CONTAINING COMPOUNDS AS BROMODOMAIN PROTEIN INHIBITORS | In4Derm Limited (GB) | 2022-05-05 | — | — | WO | disclosed |
| WO-2022090699-A1 | PYRIDONE-CONTAINING COMPOUNDS AS BROMODOMAIN PROTEIN INHIBITORS | In4Derm Limited (GB) | 2022-05-05 | — | — | WO | disclosed |