Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 19/20 | 0.53 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24397979 | 0.89 | BRD4 (0.55) | BRD4 | |
| SCHEMBL24398044 | 0.84 | BRD4 (0.55) | BRD4BRD9 | |
| SCHEMBL24398036 | 0.83 | BRD4 (0.52) | BRD4 | |
| SCHEMBL24397932 | 0.83 | BRD4 (0.56) | BRD4 | |
| SCHEMBL29564688 | 0.83 | BRD4 (0.54) | BRD4 | |
| SCHEMBL24397918 | 0.82 | BRD4 (0.58) | BRD4 | |
| SCHEMBL29564851 | 0.81 | BRD4 (0.52) | BRD4BRD9 | |
| SCHEMBL31589996 | 0.81 | BRD4 (0.66) | BRD4BRD9 | |
| SCHEMBL22588209 | 0.81 | BRD4 (0.72) | BRD4 | |
| SCHEMBL22588381 | 0.79 | BRD4 (0.52) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090699-A1 | PYRIDONE-CONTAINING COMPOUNDS AS BROMODOMAIN PROTEIN INHIBITORS | In4Derm Limited (GB) | 2022-05-05 | — | — | WO | disclosed |
| WO-2022090699-A1 | PYRIDONE-CONTAINING COMPOUNDS AS BROMODOMAIN PROTEIN INHIBITORS | In4Derm Limited (GB) | 2022-05-05 | — | — | WO | disclosed |