SCHEMBL24398484

SCHEMBL24398484

Cc1noc(C)c1-c1cc(NC(=O)c2cccc(F)c2)ccc1OC1CNC1

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 19/20 0.51
CTNNB1 P35222 19/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31199012 1.00 BCL9 (0.51) BCL9CTNNB1
SCHEMBL24398596 0.90 CTNNB1 (0.57) BCL9CTNNB1
SCHEMBL31199076 0.90 BCL9 (0.46) BCL9CTNNB1
SCHEMBL31199052 0.89 POLB (0.49) BCL9CTNNB1
SCHEMBL29619152 0.82 POLB (0.47) BCL9CTNNB1
SCHEMBL29619145 0.81 MET (0.41) BCL9CTNNB1
SCHEMBL29619086 0.81 BCL9 (0.43) BCL9CTNNB1
SCHEMBL31677951 0.76 BCL9 (0.50) BCL9CTNNB1
SCHEMBL29619161 0.76 BCL9 (0.48) BCL9CTNNB1
SCHEMBL29619045 0.76 BCL9 (0.48) BCL9CTNNB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022093850-A1 ISOXAZOLE DERIVATIVES AS MODULATORS OF THE 5-HT2A SEROTONIN RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO ARENA PHARMACEUTICALS, INC. (US) 2022-05-05 WO disclosed