Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.42 |
| ▸ | GABRA1 | P14867 | 4/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.37 |
| ▸ | DDO | Q99489 | 1/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 3/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MGLL | Q99685 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1272633 | 0.81 | BRD4 (0.38) | BRD4LMNASMN1; SMN2CA12CA1 | |
| SCHEMBL21807206 | 0.81 | LMNA (0.41) | BRD4LMNASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL24499203 | 0.80 | BRD4 (0.39) | BRD4KCNA5SMN1; SMN2 | |
| SCHEMBL1272631 | 0.78 | CA12 (0.37) | BRD4LMNASMN1; SMN2CA12CA1 | |
| SCHEMBL17240948 | 0.74 | MEN1 (0.49) | LMNASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL2005190 | 0.74 | BRD4 (0.41) | BRD4LMNASMN1; SMN2CA12CA1 | |
| SCHEMBL2005193 | 0.71 | BRD4 (0.42) | BRD4RECQLLMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL24610590 | 0.70 | BRD4 (0.33) | BRD4 | |
| SCHEMBL17240950 | 0.70 | BRD4 (0.35) | BRD4LMNASMN1; SMN2L3MBTL1KDM4E | |
| SCHEMBL20871562 | 0.69 | BRD4 (0.41) | BRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023196601-A1 | OXADIAZOLE HDAC6 INHIBITORS AND USES THEREOF | EIKONIZO THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | WO | disclosed |
| WO-2022094271-A1 | METHODS FOR TREATING CANCER | SCORPION THERAPEUTICS, INC. (US) | 2022-05-05 | — | — | WO | disclosed |