SCHEMBL24400697

SCHEMBL24400697

O=C(O)c1cc2c(nc(CN3CC=C(c4cccc(OCc5ccc(Cl)cc5F)n4)CC3)n2CC2CCO2)s1

nearest known ligand 0.58

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
GLP1R P43220 20/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30209260 1.00 GLP1R (0.58) GLP1R
SCHEMBL24147544 1.00 GLP1R (0.58) GLP1R
SCHEMBL24400979 0.93 GLP1R (0.52) GLP1R
SCHEMBL24400741 0.93 GLP1R (0.52) GLP1R
SCHEMBL25925526 0.92 GLP1R (0.55) GLP1R
SCHEMBL30209317 0.92 GLP1R (0.52) GLP1R
SCHEMBL25119864 0.92 GLP1R (0.52) GLP1R
SCHEMBL24400945 0.92 GLP1R (0.52) GLP1R
SCHEMBL24400905 0.92 GLP1R (0.52) GLP1R
SCHEMBL24400981 0.91 GLP1R (0.53) GLP1R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230203057-A1 FIVE-MEMBERED HETEROAROMATIC IMIDAZOLE COMPOUND AND USE THEREOF HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) 2023-06-29 US disclosed
EP-4155313-A1 FIVE-MEMBERED HETEROAROMATIC IMIDAZOLE COMPOUND AND USE THEREOF Hangzhou Sciwind Biosciences Co., Ltd. (CN) 2023-03-29 EP disclosed
US-11542272-B2 Five-membered heteroaryl-fused imidazole compound and application thereof HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) 2023-01-03 US disclosed
US-20220135588-A1 Five-Membered Heteroaryl-Fused Imidazole Compound And Application Thereof HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) 2022-05-05 US disclosed
CN-113831337-A GLP-1 receptor agonist, and pharmaceutical composition and use thereof 广州市恒诺康医药科技有限公司 2021-12-24 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220135588-A1 Five-Membered Heteroaryl-Fused Imidazole Compound And Application Thereof GLP1R, GIPR, GPR119 GLP1R 1/4885
US-20230203057-A1 FIVE-MEMBERED HETEROAROMATIC IMIDAZOLE COMPOUND AND USE THEREOF GLP1R, GIPR, GPR119 GLP1R 1/4885
US-11542272-B2 Five-membered heteroaryl-fused imidazole compound and application thereof GLP1R, GIPR, GPR119 GLP1R 1/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.