Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | GAA | P10253 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.53 |
| ▸ | TUBB | P07437 | 1/20 | 0.53 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.53 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.53 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.53 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.53 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.53 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.53 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.53 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13567968 | 0.84 | GAA (0.56) | MAPTRAB9AGAANPC1L3MBTL1 | |
| SCHEMBL4692835 | 0.79 | MAPT (0.45) | MAPTRAB9AGAANPC1L3MBTL1 | |
| SCHEMBL10055019 | 0.79 | MAPT (0.82) | MAPTRAB9AGAANPC1L3MBTL1 | |
| SCHEMBL5669873 | 0.79 | MAPT (0.82) | MAPTRAB9AGAANPC1L3MBTL1 | |
| SCHEMBL1844199 | 0.79 | MAPT (0.82) | MAPTRAB9AGAANPC1L3MBTL1 | |
| SCHEMBL10924995 | 0.78 | RAB9A (0.70) | MAPTRAB9AGAANPC1L3MBTL1 | |
| Hydrochloric Acid SCHEMBL9305559 | 0.77 | MAPT (0.68) | MAPTRAB9AGAANPC1L3MBTL1 | |
| SCHEMBL13567976 | 0.75 | GAA (0.47) | MAPTRAB9AGAANPC1L3MBTL1 | |
| SCHEMBL5998644 | 0.75 | MAPT (0.65) | MAPTRAB9AGAANPC1L3MBTL1 | |
| SCHEMBL22783768 | 0.74 | MAPT (0.74) | MAPTRAB9AGAANPC1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4238974-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | Adlai Nortye Biopharma Co., Ltd. (CN) | 2023-09-06 | — | — | EP | disclosed |
| WO-2022089454-A1 | HIGH-ACTIVITY WNT PATHWAY INHIBITOR COMPOUND | 杭州阿诺生物医药科技有限公司 | 2022-05-05 | — | — | WO | disclosed |