Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24401166 | 0.74 | ADORA1 (0.39) | ADORA1GRM5GPR119TP53POLB | |
| SCHEMBL24400818 | 0.74 | ADORA1 (0.38) | ADORA1GRM5ACKR3ATMGPR119 | |
| SCHEMBL1775683 | 0.71 | ADORA1 (0.43) | ADORA1GRM5ACKR3ATMGPR119 | |
| SCHEMBL4033844 | 0.71 | ATM (0.48) | ADORA1GRM5ATMGPR119ALDH1A1 | |
| SCHEMBL24401162 | 0.71 | ADORA1 (0.39) | ADORA1GRM5ALOX15GPR119TP53 | |
| SCHEMBL6298972 | 0.71 | MAPT (0.48) | ALOX15ATMPOLBALDH1A1MEN1 | |
| SCHEMBL19329569 | 0.69 | TP53 (0.42) | ADORA1GRM5ATMGPR119TP53 | |
| SCHEMBL26107555 | 0.69 | ACKR3 (0.44) | ADORA1ACKR3ATMTP53POLB | |
| SCHEMBL1174301 | 0.69 | ADORA1 (0.57) | ADORA1ALDH1A1NPSR1LMNASMN1; SMN2 | |
| SCHEMBL980137 | 0.69 | ADORA1 (0.60) | ADORA1ALOX15ALDH1A1NPSR1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230203057-A1 | FIVE-MEMBERED HETEROAROMATIC IMIDAZOLE COMPOUND AND USE THEREOF | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2023-06-29 | — | — | US | disclosed |
| US-11542272-B2 | Five-membered heteroaryl-fused imidazole compound and application thereof | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2023-01-03 | — | — | US | disclosed |
| US-20220135588-A1 | Five-Membered Heteroaryl-Fused Imidazole Compound And Application Thereof | HANGZHOU SCIWIND BIOSCIENCES CO., LTD (CN) | 2022-05-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220135588-A1 | Five-Membered Heteroaryl-Fused Imidazole Compound And Application Thereof | GLP1R, GIPR, GPR119 | ADORA1 1439/4885GRM5 259/4885ALOX15 2801/4885 |
| US-20230203057-A1 | FIVE-MEMBERED HETEROAROMATIC IMIDAZOLE COMPOUND AND USE THEREOF | GLP1R, GIPR, GPR119 | ADORA1 1083/4885GRM5 256/4885ALOX15 2699/4885 |
| US-11542272-B2 | Five-membered heteroaryl-fused imidazole compound and application thereof | GLP1R, GIPR, GPR119 | ADORA1 1439/4885GRM5 259/4885ALOX15 2801/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.