SCHEMBL24401659

SCHEMBL24401659

O=c1c2ccccc2sc2cc3c(cc12)-c1ccccc1C31c2ccccc2-c2cc3c4ccccc4n(-c4ccccc4)c3cc21

nearest known ligand 0.38

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.38
L3MBTL1 Q9Y468 3/20 0.38
ATM Q13315 1/20 0.38
ALDH1A1 P00352 2/20 0.34
MAPT P10636 2/20 0.34
TDP1 Q9NUW8 2/20 0.34
NPC1 O15118 1/20 0.34
RAB9A P51151 1/20 0.34
POLB P06746 1/20 0.31
HSD17B10 Q99714 1/20 0.30
PDE1B Q01064 1/20 0.30
PDE3A Q14432 1/20 0.30
PDE11A Q9HCR9 1/20 0.30
MAOA P21397 1/20 0.30
MAOB P27338 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24401662 0.97 KDM4E (0.37) KDM4EL3MBTL1ATMALDH1A1MAPT
SCHEMBL24401415 0.88 MAPT (0.34) KDM4EL3MBTL1ALDH1A1MAPTTDP1
SCHEMBL24401409 0.85 KDM4E (0.38) KDM4EL3MBTL1ATMALDH1A1MAPT
SCHEMBL24401430 0.85 KDM4E (0.38) KDM4EL3MBTL1ATMALDH1A1MAPT
SCHEMBL17380959 0.84 KDM4E (0.53) KDM4EL3MBTL1ATMALDH1A1MAPT
SCHEMBL20129527 0.84 KDM4E (0.53) KDM4EL3MBTL1ATMALDH1A1MAPT
SCHEMBL23058894 0.84 KDM4E (0.53) KDM4EL3MBTL1ATMALDH1A1MAPT
SCHEMBL14681689 0.83 KDM4E (0.46) KDM4EL3MBTL1ATMALDH1A1POLB
SCHEMBL20199493 0.83 KDM4E (0.51) KDM4EL3MBTL1ATMALDH1A1MAPT
SCHEMBL14681702 0.82 KDM4E (0.47) KDM4EL3MBTL1ATMALDH1A1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220140249-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CANON KABUSHIKI KAISHA (JP) 2022-05-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220140249-A1 ORGANIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE CDYL, MRPL38, CDYL2 KDM4E 3526/4885L3MBTL1 267/4885ATM 2065/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.