Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K12 | Q12852 | 7/20 | 0.36 |
| ▸ | GBA1 | P04062 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12337631 | 1.00 | MAP3K12 (0.36) | MAP3K12GBA1GAA | |
| SCHEMBL23867310 | 0.92 | GBA1 (0.39) | MAP3K12GBA1 | |
| SCHEMBL25608577 | 0.92 | GBA1 (0.39) | MAP3K12GBA1 | |
| SCHEMBL26157149 | 0.88 | GAA (0.38) | MAP3K12GBA1GAA | |
| SCHEMBL13561489 | 0.86 | MAP3K12 (0.36) | MAP3K12GBA1 | |
| SCHEMBL18775524 | 0.86 | MAP3K12 (0.36) | MAP3K12GBA1 | |
| SCHEMBL24402945 | 0.86 | MAP3K12 (0.36) | MAP3K12GBA1 | |
| SCHEMBL24402949 | 0.81 | MAP3K12 (0.34) | MAP3K12GBA1 | |
| SCHEMBL22360705 | 0.81 | MAP3K12 (0.37) | MAP3K12GBA1 | |
| SCHEMBL18776511 | 0.81 | MAP3K12 (0.34) | MAP3K12GBA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022090481-A1 | SUBSTITUTED 1H-PYRAZOLO[4,3-C]PYRIDINES AND DERIVATIVES AS EGFR INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2022-05-05 | — | — | WO | disclosed |