SCHEMBL26157149

SCHEMBL26157149

CCCN1C[C@@H]2C[C@H]1CN2CCOC

nearest known ligand 0.38

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.38
MAP3K12 Q12852 7/20 0.36
GBA1 P04062 3/20 0.35
TLR7 Q9NYK1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25608577 0.92 GBA1 (0.39) MAP3K12GBA1
SCHEMBL23867310 0.92 GBA1 (0.39) MAP3K12GBA1
SCHEMBL12337631 0.88 MAP3K12 (0.36) GAAMAP3K12GBA1
SCHEMBL24401976 0.88 MAP3K12 (0.36) GAAMAP3K12GBA1
SCHEMBL24402945 0.86 MAP3K12 (0.36) MAP3K12GBA1
SCHEMBL18775524 0.86 MAP3K12 (0.36) MAP3K12GBA1
SCHEMBL13561489 0.86 MAP3K12 (0.36) MAP3K12GBA1
SCHEMBL24772842 0.85 GAA (0.42) GAAGBA1
SCHEMBL12716569 0.81 GAA (0.37) GAA
SCHEMBL22493222 0.81 GAA (0.37) GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023093728-A1 BRM SELECTIVE DEGRADATION AGENT COMPOUND AND USE THEREOF 江苏先声药业有限公司 2023-06-01 WO disclosed