SCHEMBL2440307

SCHEMBL2440307

C[C@H]1C[N]CCO1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2442385 1.00
SCHEMBL392279 1.00
SCHEMBL8650903 0.72
SCHEMBL1484449 0.72
SCHEMBL8751150 0.72
SCHEMBL232761 0.72
SCHEMBL8751032 0.72
SCHEMBL3130602 0.71
SCHEMBL9426579 0.71
SCHEMBL4624350 0.67

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20130040934-A1 SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES UNIVERSITY OF BASEL (CH) 2013-02-14 US claimed
EP-2547684-A1 SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES University of Basel (CH) 2013-01-23 EP claimed
WO-2011114275-A1 SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES UNIVERSITY OF BASEL (CH) 2011-09-22 WO claimed
CN-117858707-A CBL-B modulators and uses thereof 林伯士克莱奥公司 2024-04-09 CN disclosed
US-20230192704-A1 MONOCARBOXYLIC ACID TRANSPORTER 4 (MCT4) MODULATORS AND USES THEREOF TEON THERAPEUTICS INC (US) 2023-06-22 US disclosed
US-20130040934-A1 SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES UNIVERSITY OF BASEL (CH) 2013-02-14 US disclosed
EP-2547684-A1 SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES University of Basel (CH) 2013-01-23 EP disclosed
WO-2011114275-A1 SPIROCYCLIC COMPOUNDS AND THEIR USE AS THERAPEUTIC AGENTS AND DIAGNOSTIC PROBES UNIVERSITY OF BASEL (CH) 2011-09-22 WO disclosed
EP-0656365-B1 Substituted 2beta-morpholinoandrostane derivatives AKZO NOBEL NV (NL) 1997-04-09 EP disclosed
US-5593983-A PREPARATION BY REACTING SUBSTITUTED /THIO/MORPHOLINE OR SALT AND 2,3-EPOXYANDROSTANE OR 2,3-EPOXY-19-NOR-ANDROSTANE; USE TO INDUCE ANESTHESIA AKZO NOBEL N.V. (NL) 1997-01-14 US disclosed
EP-0656365-A1 Substituted 2beta-morpholinoandrostane derivatives Akzo Nobel N.V. (NL) 1995-06-07 EP disclosed