⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1484449 | 0.76 | — | — | |
| SCHEMBL6751694 | 0.73 | — | — | |
| SCHEMBL2442385 | 0.72 | — | — | |
| SCHEMBL4921880 | 0.72 | — | — | |
| SCHEMBL2440307 | 0.72 | — | — | |
| SCHEMBL392279 | 0.72 | — | — | |
| SCHEMBL6750303 | 0.72 | — | — | |
| SCHEMBL4624350 | 0.71 | — | — | |
| SCHEMBL6752704 | 0.71 | — | — | |
| SCHEMBL6752052 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5773437-A | UROGENITAL DISORDERS SUCH AS DYSURIA | NIPPON CHEMIPHAR CO., LTD. (JP) | 1998-06-30 | — | — | US | disclosed |
| US-5643925-A | COGNITION ACTIVATORS AND NERVE GROWTH FACTORS | SANKYO COMPANY, LIMITED (JP) | 1997-07-01 | — | — | US | disclosed |
| US-5614521-A | NERVE GROWTH FACTOR | SANKYO COMPANY, LIMITED (JP) | 1997-03-25 | — | — | US | disclosed |
| EP-0501656-A2 | New benzene derivatives having (NGF) production-promoting activity | Sankyo Company Limited (JP) | 1992-09-02 | — | — | EP | disclosed |
| US-4172945-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-10-30 | — | — | US | disclosed |
| US-4156789-A | INTERMEDIATES, ANTIFIBRILLATORY AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4156723-A | HYPOTENSIVE | E. R. SQUIBB & SONS, INC. (US) | 1979-05-29 | — | — | US | disclosed |
| US-4138497-A | Indanpentol derivatives for treating hypertension | E. R. SQUIBB & SONS, INC. (US) | 1979-02-06 | — | — | US | disclosed |
| US-4127578-A | Diene intermediates for indantetrols | E. R. SQUIBB & SONS, INC. (US) | 1978-11-28 | — | — | US | disclosed |
| US-4113726-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1978-09-12 | — | — | US | disclosed |
| US-4053596-A | HYPOTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-10-11 | — | — | US | disclosed |
| US-4044040-A | HYPERTENSIVE AGENTS | E. R. SQUIBB & SONS, INC. (US) | 1977-08-23 | — | — | US | disclosed |
| US-4012373-A | ANTIINFLAMMATORY, CNS DEPRESSANTS | E. R. SQUIBB & SONS, INC. (US) | 1977-03-15 | — | — | US | disclosed |
| US-3984419-A | HYPOTENSIVES | E. R. SQUIBB & SONS, INC. (US) | 1976-10-05 | — | — | US | disclosed |
| US-3982021-A | Compositions for the treatment of coronary diseases containing tetrahydronaphthyloxy-aminopropanols | E. R. SQUIBB & SONS, INC. (US) | 1976-09-21 | — | — | US | disclosed |
| US-3979444-A | CENTRAL NERVOUS SYSTEM DEPRESSANTS, HYPOTENSIVES | THE UPJOHN COMPANY (US) | 1976-09-07 | — | — | US | disclosed |
| US-3965180-A | CNS DEPRESSANT | THE UPJOHN COMPANY (US) | 1976-06-22 | — | — | US | disclosed |
| US-3956285-A | CORONARY DISEASES, WATER SOFTENERS, CORROSION INHIBITORS | E. R. SQUIBB & SONS, INC. (US) | 1976-05-11 | — | — | US | disclosed |
| US-3943149-A | HYPOCHOLESTEREMIC, ANTIINFLAMMATORY | E. R. SQUIBB & SONS, INC. (US) | 1976-03-09 | — | — | US | disclosed |
| US-3935267-A | CARDIOVASCULAR DISORDERS | E. R. SQUIBB & SONS, INC. (US) | 1976-01-27 | — | — | US | disclosed |