SCHEMBL2440342

SCHEMBL2440342

O=C1CCCN(C(=O)OCc2ccccc2)C1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TMEM97 Q5BJF2 14/20 0.57
SIGMAR1 Q99720 14/20 0.57
MEN1 O00255 2/20 0.56
KMT2A Q03164 2/20 0.56
NPSR1 Q6W5P4 1/20 0.56
SMN1; SMN2 Q16637 2/20 0.55
NPC1 O15118 2/20 0.55
RAB9A P51151 2/20 0.55
CYP2C19 P33261 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.50
ALDH1A1 P00352 1/20 0.48
GAA P10253 1/20 0.48
MAPT P10636 1/20 0.48
HPGD P15428 1/20 0.48
ALOX15 P16050 1/20 0.48
HSD17B10 Q99714 1/20 0.48
CHRM4 P08173 1/20 0.47
HTR1A P08908 1/20 0.47
CHRM5 P08912 1/20 0.47
ADRA2A P08913 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5417320 0.96 MEN1 (0.55) TMEM97SIGMAR1MEN1KMT2ANPSR1
SCHEMBL18084738 0.94 MEN1 (0.53) TMEM97SIGMAR1MEN1KMT2ANPSR1
SCHEMBL265902 0.91 MEN1 (0.58) TMEM97SIGMAR1MEN1KMT2ANPSR1
SCHEMBL3602428 0.91 MEN1 (0.62) TMEM97SIGMAR1MEN1KMT2ANPSR1
SCHEMBL3612576 0.89 MEN1 (0.59) TMEM97SIGMAR1MEN1KMT2ANPSR1
SCHEMBL467515 0.89 MEN1 (0.59) TMEM97SIGMAR1MEN1KMT2ANPSR1
SCHEMBL15010930 0.87 CYP2C19 (0.46) TMEM97SIGMAR1MEN1KMT2ANPSR1
SCHEMBL1488412 0.85 KMT2A (0.60) TMEM97SIGMAR1MEN1KMT2ANPSR1
SCHEMBL8323054 0.84 TMEM97 (0.56) TMEM97SIGMAR1MEN1KMT2ANPSR1
SCHEMBL16078941 0.84 TMEM97 (0.56) TMEM97SIGMAR1MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 324 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119574680-A Mass spectrum detection method for N-heterocyclic ketone and/or N-heterocyclic chiral amino compound and application thereof 北京衍微科技有限公司 2025-03-07 CN claimed
CN-119023611-A Real-time monitoring method for ketone-amine conversion reaction process and application thereof 北京衍微科技有限公司 2024-11-26 CN claimed
CN-116042560-A Mutant of recombinant aminotransferase and application thereof 清华大学 2023-05-02 CN claimed
CN-107586798-A The method that living things catalysis prepares the hydroxy piperidine of (S) 1 N benzene methoxycarbonyl group 3 上海合全药物研发有限公司 2018-01-16 CN claimed
CN-107574194-A The method that living things catalysis prepares the hydroxy piperidine of (R) 1 N benzene methoxycarbonyl group 3 上海合全药物研发有限公司 2018-01-12 CN claimed
EP-2623593-B1 NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE KANEKA CORP (JP) 2017-07-12 EP claimed
EP-2684953-B1 MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME KANEKA CORP (JP) 2017-06-28 EP claimed
EP-2623595-B1 NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF KANEKA CORP (JP) 2016-11-02 EP claimed
US-9481870-B2 Nucleic acid encoding a polypeptide having aminotransferase activity, vectors and host cells comprising the nucleic acid KANEKA CORPORATION (JP) 2016-11-01 US claimed
CN-103534353-B Modification type aminopherase, its gene and utilize their manufacture method of optical activity amino-compound 株式会社钟化 2016-08-17 CN claimed
US-9029113-B2 Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same KANEKA CORPORATION (JP) 2015-05-12 US claimed
CN-103534350-A Novel aminotransferase exhibiting high activity for glutamic acid, gene encoding the same, and method for using the same KANEKA CORP 2014-01-22 CN claimed
CN-103534353-A Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same KANEKA CORP 2014-01-22 CN claimed
EP-2684953-A1 MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME Kaneka Corporation (JP) 2014-01-15 EP claimed
US-20140004575-A1 MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME KANEKA CORPORATION (JP) 2014-01-02 US claimed
US-20130210092-A1 Novel Transaminase, Gene Encoding the Same, and Method Using Them KANEKA CORPORATION (JP) 2013-08-15 US claimed
EP-2623593-A1 NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE Kaneka Corporation (JP) 2013-08-07 EP claimed
EP-2623595-A1 NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF Kaneka Corporation (JP) 2013-08-07 EP claimed
US-20130196389-A1 NOVEL TRANSAMINASE EXHIBITING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR USING THEM KANEKA CORPORATION (JP) 2013-08-01 US claimed
CN-103140580-A Novel aminotransferase, gene encoding the same, and method for using the same KANEKA CORP 2013-06-05 CN claimed