SCHEMBL265902

SCHEMBL265902

O=C1CCN(C(=O)OCc2ccccc2)C1

nearest known ligand 0.60

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.58
KMT2A Q03164 2/20 0.58
NPSR1 Q6W5P4 1/20 0.58
SMN1; SMN2 Q16637 2/20 0.57
NPC1 O15118 2/20 0.57
RAB9A P51151 2/20 0.57
TMEM97 Q5BJF2 8/20 0.55
SIGMAR1 Q99720 8/20 0.55
CYP2C19 P33261 1/20 0.55
ALDH1A1 P00352 1/20 0.53
GAA P10253 1/20 0.53
MAPT P10636 1/20 0.53
HPGD P15428 1/20 0.53
ALOX15 P16050 1/20 0.53
HSD17B10 Q99714 1/20 0.53
L3MBTL1 Q9Y468 1/20 0.52
PTGDR2 Q9Y5Y4 4/20 0.51
DHFR P00374 1/20 0.51
KDR P35968 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2440342 0.91 TMEM97 (0.57) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL61861 0.91 KMT2A (0.66) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL5417320 0.90 MEN1 (0.55) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL18084738 0.89 MEN1 (0.53) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL1488412 0.87 KMT2A (0.60) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL467515 0.85 MEN1 (0.59) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL15067221 0.84 MEN1 (0.61) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL3614455 0.84 MEN1 (0.58) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL541411 0.84 MEN1 (0.57) MEN1KMT2ANPSR1SMN1; SMN2NPC1
SCHEMBL324228 0.84 TMEM97 (0.67) MEN1KMT2ANPSR1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 577 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109096415-B Olefin polymerization catalyst component, process for producing the same, olefin polymerization catalyst, and process for producing olefin polymer 中国石油化工股份有限公司 2021-03-16 CN claimed
CN-106497996-B Enzymatic preparation method of chiral alcohol 凯莱英医药集团(天津)股份有限公司 2021-01-12 CN claimed
CN-109096416-B Olefin polymerization catalyst component, process for producing the same, olefin polymerization catalyst, and process for producing olefin polymer 中国石油化工股份有限公司 2020-11-10 CN claimed
EP-2623593-B1 NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE KANEKA CORP (JP) 2017-07-12 EP claimed
EP-2684953-B1 MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME KANEKA CORP (JP) 2017-06-28 EP claimed
EP-2623595-B1 NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF KANEKA CORP (JP) 2016-11-02 EP claimed
US-9481870-B2 Nucleic acid encoding a polypeptide having aminotransferase activity, vectors and host cells comprising the nucleic acid KANEKA CORPORATION (JP) 2016-11-01 US claimed
CN-103534353-B Modification type aminopherase, its gene and utilize their manufacture method of optical activity amino-compound 株式会社钟化 2016-08-17 CN claimed
CN-103140580-B Aminotransferase, gene encoding the same, and method for using the same KANEKA CORP. (JP) 2016-06-01 CN claimed
CN-103534350-B Aminotransferase exhibiting high activity for glutamic acid, gene encoding the same, and method for using the same KANEKA CORP. (JP) 2016-03-09 CN claimed
US-9029113-B2 Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same KANEKA CORPORATION (JP) 2015-05-12 US claimed
CN-103534350-A Novel aminotransferase exhibiting high activity for glutamic acid, gene encoding the same, and method for using the same KANEKA CORP 2014-01-22 CN claimed
CN-103534353-A Modified aminotransferase, gene thereof, and method for producing optically active amino compound using same KANEKA CORP 2014-01-22 CN claimed
EP-2684953-A1 MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME Kaneka Corporation (JP) 2014-01-15 EP claimed
US-20140004575-A1 MODIFIED AMINOTRANSFERASE, GENE THEREOF, AND METHOD FOR PRODUCING OPTICALLY ACTIVE AMINO COMPOUND USING SAME KANEKA CORPORATION (JP) 2014-01-02 US claimed
US-20130210092-A1 Novel Transaminase, Gene Encoding the Same, and Method Using Them KANEKA CORPORATION (JP) 2013-08-15 US claimed
EP-2623593-A1 NOVEL AMINOTRANSFERASE AND GENE ENCODING SAME, AND USE OF THE AMINOTRANSFERASE AND THE GENE Kaneka Corporation (JP) 2013-08-07 EP claimed
EP-2623595-A1 NOVEL TRANSAMINASE SHOWING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR UTILIZATION THEREOF Kaneka Corporation (JP) 2013-08-07 EP claimed
US-20130196389-A1 NOVEL TRANSAMINASE EXHIBITING HIGH ACTIVITY FOR GLUTAMIC ACID, GENE ENCODING SAME, AND METHOD FOR USING THEM KANEKA CORPORATION (JP) 2013-08-01 US claimed
CN-103140580-A Novel aminotransferase, gene encoding the same, and method for using the same KANEKA CORP 2013-06-05 CN claimed