Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 14/20 | 0.71 |
| ▸ | CSNK1D | P48730 | 5/20 | 0.71 |
| ▸ | CSNK1E | P49674 | 4/20 | 0.71 |
| ▸ | MAPK13 | O15264 | 9/20 | 0.65 |
| ▸ | MAPK12 | P53778 | 9/20 | 0.65 |
| ▸ | MAPK11 | Q15759 | 9/20 | 0.65 |
| ▸ | GCGR | P47871 | 7/20 | 0.65 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.54 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.54 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.54 |
| ▸ | FRK | P42685 | 1/20 | 0.54 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.54 |
| ▸ | GSK3B | P49841 | 1/20 | 0.54 |
| ▸ | PTK6 | Q13882 | 1/20 | 0.54 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.54 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.53 |
| ▸ | RAF1 | P04049 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18960509 | 0.93 | MAPK14 (0.83) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL17002222 | 0.86 | MAPK14 (0.76) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL17002226 | 0.83 | MAPK14 (1.00) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL17002318 | 0.81 | MAPK14 (1.00) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL5194917 | 0.81 | TEK (0.66) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL5184633 | 0.81 | MAPK14 (0.70) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL6971902 | 0.81 | MAPK14 (0.68) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL5197068 | 0.81 | MAPK14 (0.65) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL2650684 | 0.79 | MAPK11 (1.00) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 | |
| SCHEMBL17002221 | 0.79 | MAPK14 (0.85) | MAPK14CSNK1DCSNK1EMAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102207-B1 | 2,4,5-TRI-SUBSTITUTED AZOLE-BASED CASEIN KINASE 1 INHIBITORS AS INDUCERS FOR CARDIOMYOGENESIS | AGENCY SCIENCE TECH & RES (SG) | 2022-05-11 | — | — | EP | disclosed |