Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.51 |
| ▸ | PPARA | Q07869 | 7/20 | 0.40 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.40 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.40 |
| ▸ | PPARG | P37231 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MMP9 | P14780 | 1/20 | 0.35 |
| ▸ | MMP8 | P22894 | 1/20 | 0.35 |
| ▸ | MMP13 | P45452 | 1/20 | 0.35 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3686994 | 0.88 | PPARA (0.56) | SLC2A1PPARAABCB11CYP1A2CYP3A4 | |
| SCHEMBL14397663 | 0.76 | PPARA (0.41) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL14397268 | 0.76 | PPARA (0.41) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL2440481 | 0.75 | PPARA (0.44) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL12980551 | 0.75 | SLC2A1 (0.43) | SLC2A1CYP1A2CYP3A4TSHRLMNA | |
| SCHEMBL14398600 | 0.75 | PPARA (0.41) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL12426828 | 0.72 | PPARA (0.45) | PPARAABCB11CYP1A2CYP3A4TSHR | |
| SCHEMBL27503068 | 0.72 | SLC2A1 (0.69) | SLC2A1CYP1A2MMP9MMP13MAPT | |
| SCHEMBL1728974 | 0.71 | SLC2A1 (0.55) | SLC2A1TSHRPPARGLMNAMAPT | |
| SCHEMBL1729187 | 0.71 | SLC2A1 (0.55) | SLC2A1TSHRPPARGLMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1433786-B1 | Benzoxazole compound and pharmaceutical composition containing the compound | KOWA CO (JP) | 2011-09-21 | — | — | EP | disclosed |