Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.54 |
| ▸ | PTPRC | P08575 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | MLNR | O43193 | 1/20 | 0.38 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | DRD2 | P14416 | 1/20 | 0.38 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.38 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | DRD1 | P21728 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29469450 | 1.00 | PDK2 (0.54) | PDK2PTPRCOPRM1OPRD1MLNR | |
| SCHEMBL29371626 | 1.00 | PDK2 (0.54) | PDK2PTPRCOPRM1OPRD1MLNR | |
| SCHEMBL14174206 | 0.96 | PDK2 (0.51) | PDK2PTPRCOPRM1OPRD1MLNR | |
| SCHEMBL21436406 | 0.94 | PDK2 (0.50) | PDK2PTPRCOPRM1OPRD1MLNR | |
| SCHEMBL30631789 | 0.93 | PDK2 (0.49) | PDK2PTPRC | |
| SCHEMBL431791 | 0.93 | PDK2 (0.49) | PDK2PTPRC | |
| SCHEMBL431255 | 0.93 | PDK2 (0.49) | PDK2PTPRC | |
| SCHEMBL17656925 | 0.91 | PDK2 (0.50) | PDK2PTPRCOPRM1OPRD1TDP1 | |
| SCHEMBL204806 | 0.89 | PDK2 (0.44) | PDK2PTPRCHTR2BCYP2A6PGR | |
| SCHEMBL29403081 | 0.89 | PDK2 (0.44) | PDK2PTPRCHTR2BCYP2A6PGR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2243 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014744-B | Method for preparing 2-bromo-9, 9-dimethylfluorene by catalysis | 中唯炼焦技术国家工程研究中心有限责任公司 | 2024-07-09 | — | — | CN | claimed |
| CN-115894484-B | Isoquinoline quinoline compound and preparation method and application thereof | 烟台九目化学股份有限公司 | 2024-03-19 | — | — | CN | claimed |
| CN-115894484-A | Isoquinoline compound and preparation method and application thereof | 烟台九目化学股份有限公司 | 2023-04-04 | — | — | CN | claimed |
| CN-115850022-A | Synthesis method of 9, 9-dimethyl-2-bromofluorene | 郑州圣壹新材料科技有限公司 | 2023-03-28 | — | — | CN | claimed |
| CN-111170957-B | Preparation method of hole transport material composition containing benzoxazole and thiazole groups | 上海百豪新材料有限公司 | 2023-03-21 | — | — | CN | claimed |
| CN-114957251-A | High-performance photoelectric material, preparation method and organic electroluminescent device | 烟台九目化学股份有限公司 | 2022-08-30 | — | — | CN | claimed |
| CN-113336622-B | Fluorene derivative with AIE characteristic, preparation method and application | 辽宁师范大学 | 2022-06-10 | — | — | CN | claimed |
| CN-114014744-A | Method for preparing 2-bromo-9, 9-dimethylfluorene through catalysis | 中唯炼焦技术国家工程研究中心有限责任公司 | 2022-02-08 | — | — | CN | claimed |
| CN-113336622-A | Fluorene derivative with AIE characteristic, preparation method and application | 辽宁师范大学 | 2021-09-03 | — | — | CN | claimed |
| CN-112500326-A | Hole transport/exciton blocking material with high triplet state energy level and high glass transition temperature, preparation and application | 华南理工大学 | 2021-03-16 | — | — | CN | claimed |
| CN-109251148-A | Coating molecular structure, production method and corresponding OLED device | 武汉华星光电半导体显示技术有限公司 | 2019-01-22 | — | — | CN | claimed |
| CN-103204797-B | The arylamine class luminous organic material of dihydro pentacene and preparation method | Jilin Optical and Electronic Materials Co., Ltd. (CN) | 2016-01-20 | — | — | CN | claimed |
| CN-102718625-B | Preparation method for 9, 9,-dimethyl-2-bromofluorene | SHANGHAI YINSHENG BIOTECHNOLOGY CO LTD | 2015-02-18 | — | — | CN | claimed |
| CN-101973895-B | Method for synthesizing N,N'-diphenyl-N-(9,9-dimethyl-2-fluorenyl)-N'-(9',9'-dimethyl-7'-bromo-2'-fluorenyl)-benzidine | TIANJIN BASECHEM TECHNOLOGY CO LTD | 2013-07-17 | — | — | CN | claimed |
| CN-101987823-B | N, N'-diphenyl-N-(9, 9-dimethyl-2-fluorenyl)-N'-(9, 9-dimethyl-7'-(2''-naphthyl)-2'-fluorenyl)-benzidine and synthesis method thereof | TIANJIN BASECHEM TECHNOLOGY CO LTD | 2013-05-22 | — | — | CN | claimed |
| CN-102718625-A | Preparation method for 9, 9,-dimethyl-2-bromofluorene | SHANGHAI YINSHENG BIO TECHNOLOGY CO LTD | 2012-10-10 | — | — | CN | claimed |
| CN-102030702-B | Hole-transporting material and synthesis method thereof | TIANJIN BAISIKANG SCIENCE AND TECHNOLOGY CO LTD | 2012-01-04 | — | — | CN | claimed |
| CN-102030702-A | Hole-transporting material and synthesis method thereof | TIANJIN BAISIKANG SCIENCE AND TECHNOLOGY CO LTD | 2011-04-27 | — | — | CN | claimed |
| CN-101987823-A | N, N'-diphenyl-N-(9, 9-dimethyl-2-fluorenyl)-N'-(9, 9-dimethyl-7'-(2''-naphthyl)-2'-fluorenyl)-benzidine and synthesis method thereof | TIANJIN BASECHEM TECHNOLOGY CO LTD | 2011-03-23 | — | — | CN | claimed |
| CN-101973895-A | Method for synthesizing N,N'-diphenyl-N-(9,9-dimethyl-2-fluorenyl)-N'-(9',9'-dimethyl-7'-bromo-2'-fluorenyl)-benzidine | TIANJIN BASECHEM TECHNOLOGY CO LTD | 2011-02-16 | — | — | CN | claimed |