SCHEMBL204806

SCHEMBL204806

CC1(C)c2cc(Br)ccc2-c2ccc(Br)cc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 1/20 0.44
S100A4 P26447 1/20 0.41
CA1 P00915 1/20 0.39
CA2 P00918 1/20 0.39
CA4 P22748 1/20 0.39
CA7 P43166 1/20 0.39
CA9 Q16790 1/20 0.39
AKR1A1 P14550 1/20 0.39
AKR1B1 P15121 1/20 0.39
TDP2 O95551 1/20 0.38
PGR P06401 2/20 0.36
PTPRC P08575 1/20 0.35
METAP1 P53582 1/20 0.35
BCL2 P10415 1/20 0.34
MCL1 Q07820 1/20 0.34
HTR2B P41595 1/20 0.34
SIGMAR1 Q99720 1/20 0.34
MALT1 Q9UDY8 1/20 0.33
TGM2 P21980 1/20 0.33
CES1 P23141 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29403081 1.00 PDK2 (0.44) PDK2S100A4CA1CA2CA4
SCHEMBL29587737 1.00 PDK2 (0.44) PDK2S100A4CA1CA2CA4
SCHEMBL5063493 0.95 PDK2 (0.42) PDK2S100A4CA1CA2CA4
SCHEMBL29294792 0.95 PDK2 (0.42) PDK2S100A4CA1CA2CA4
SCHEMBL29458875 0.95 PDK2 (0.42) PDK2S100A4CA1CA2CA4
SCHEMBL5013191 0.95 PDK2 (0.42) PDK2S100A4CA1CA2CA4
SCHEMBL10227289 0.93 PDK2 (0.41) PDK2S100A4CA1CA2CA4
SCHEMBL1648023 0.91 PDK2 (0.40) PDK2S100A4CA1CA2CA4
SCHEMBL1649907 0.91 PDK2 (0.40) PDK2S100A4CA1CA2CA4
SCHEMBL14508381 0.91 PDK2 (0.40) PDK2S100A4CA1CA2CA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 985 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12365765-B2 Poly(arylene sulfide) polymers and corresponding polymer compositions and articles SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2025-07-22 US claimed
EP-4045568-B1 POLY(ARYLENE SULFIDE) POLYMERS AND CORRESPONDING POLYMER COMPOSITIONS AND ARTICLES SOLVAY SPECIALTY POLYMERS USA (US) 2025-05-21 EP claimed
CN-117924735-A Cobalt coordination two-dimensional MOFs and preparation method thereof 吉林大学 2024-04-26 CN claimed
CN-114402013-B Poly (arylene sulfide) polymer and corresponding polymer composition and article 索尔维特殊聚合物美国有限责任公司 2024-04-19 CN claimed
CN-115611792-B Organic double-free radical single-molecule device stable at room temperature and preparation method thereof 电子科技大学 2024-03-22 CN claimed
US-11784305-B2 Negative electrode including silicon nanoparticles having a carbon coating thereon GM Global Technology Operations LLC (US) 2023-10-10 US claimed
CN-115624867-B Preparation method of filter membrane 佛山(华南)新材料研究院 2023-03-07 CN claimed
CN-115624867-A Preparation method of high-performance filter membrane 佛山(华南)新材料研究院 2023-01-20 CN claimed
CN-115611792-A Organic diradical monomolecular device stable at room temperature and preparation method thereof 电子科技大学 2023-01-17 CN claimed
US-20220380546-A1 POLY(ARYLENE SULFIDE) POLYMERS AND CORRESPONDING POLYMER COMPOSITIONS AND ARTICLES SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2022-12-01 US claimed
CN-114402013-A Poly (aryl sulfide) polymers and corresponding polymer compositions and articles 索尔维特殊聚合物美国有限责任公司 2022-04-26 CN claimed
WO-2021074051-A1 POLY(ARYLENE SULFIDE) POLYMERS AND CORRESPONDING POLYMER COMPOSITIONS AND ARTICLES SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2021-04-22 WO claimed
CN-104650118-B Preparation method and application of derivative by taking dibenzofuran as skeleton core 吉林奥来德光电材料股份有限公司 2017-01-11 CN claimed
CN-104629719-A Fluorene derivatives and applications thereof in electroluminescent devices JILIN OPTICAL & ELECTRONIC MATERIALS CO LTD 2015-05-20 CN claimed
US-20260146125-A1 LADDER POLYMERS AND IMPROVED METHODS OF MAKING THE SAME OSMOSES INC. (US) 2026-05-28 US disclosed
US-20260070931-A1 METHOD FOR MANUFACTURING ELECTROPHILIC SUBSTITUTED AROMATIC COMPOUND FUJIFILM CORPORATION (JP) 2026-03-12 US disclosed
EP-4601774-A1 LADDER POLYMERS AND IMPROVED METHODS OF MAKING THE SAME Osmoses Inc. (US) 2025-08-20 EP disclosed
WO-2004020372-A1 FLUORENE COMPOUND AND ORGANIC LUMINESCENT DEVICE USING THE SAME CANON KABUSHIKI KAISHA (JP) 2004-03-11 WO disclosed
US-20030065226-A1 Method for preparing bromofluorenes ADCHEMCO CORPORATION (JP) 2003-04-03 US disclosed
EP-1298117-A2 Method for preparing bromofluorenes Adchemco Corporation (JP) 2003-04-02 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065226-A1 Method for preparing bromofluorenes FLNB, AFF2, BRPF1 PDK2 2076/4885S100A4 3799/4885CA1 4039/4885
US-20260146125-A1 LADDER POLYMERS AND IMPROVED METHODS OF MAKING THE SAME CCRL2, GJB2, BCR PDK2 4322/4885S100A4 1304/4885CA1 2291/4885
US-20260070931-A1 METHOD FOR MANUFACTURING ELECTROPHILIC SUBSTITUTED AROMATIC COMPOUND TRPA1, ALK, MAFK PDK2 4002/4885S100A4 3528/4885CA1 3295/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.