Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRIM24 | O15164 | 1/20 | 0.42 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.39 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.39 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30630797 | 1.00 | TRIM24 (0.42) | TRIM24TRIM33MEN1KMT2AALOX15 | |
| SCHEMBL1356310 | 0.74 | ALDH1A1 (0.44) | ALDH1A1CYP2A6CYP11B1KDM4EKCNJ1 | |
| SCHEMBL21873379 | 0.73 | JMJD6 (0.41) | MEN1KMT2AALDH1A1CYP11B1KDM4E | |
| SCHEMBL16880609 | 0.73 | HSP90AA1 (0.51) | ALDH1A1CYP11B1KDM4EPOLB | |
| SCHEMBL30630858 | 0.73 | HSP90AA1 (0.51) | ALDH1A1CYP11B1KDM4EPOLB | |
| SCHEMBL31607177 | 0.72 | ALDH1A1 (0.43) | ALDH1A1CYP2A6CYP11B1KDM4EKCNJ1 | |
| SCHEMBL31607172 | 0.72 | ALDH1A1 (0.43) | ALDH1A1CYP2A6CYP11B1KDM4EKCNJ1 | |
| SCHEMBL31607175 | 0.72 | ALDH1A1 (0.43) | ALDH1A1CYP2A6CYP11B1KDM4EKCNJ1 | |
| SCHEMBL14762040 | 0.70 | AOC3 (0.37) | MEN1KMT2AALDH1A1CYP2A6CYP11B1 | |
| SCHEMBL5181284 | 0.70 | DYRK1A (0.46) | TRIM24TRIM33ALOX15ALDH1A1CYP2A6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144847-A1 | HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF | ELLIPSES PHARMA LTD (GB) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144847-A1 | HETEROCYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION COMPRISING SAME, PREPARATION METHOD THEREFOR, AND USE THEREOF | NOTUM, FURIN, CYP4A11 | TRIM24 4398/4885TRIM33 4701/4885MEN1 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.