SCHEMBL24410004

SCHEMBL24410004

NCOCCOCCOCC(=O)N[C@@H](CCCCNC(=O)CN1CCN(CC(=O)O)CN(CC(=O)O)CCN(CC(=O)O)C1)C(N)=O

nearest known ligand 0.40

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
FOLH1 Q04609 11/20 0.40
GLP1R P43220 8/20 0.38
ALB P02768 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24422578 0.81 ALB (0.46) FOLH1GLP1RALB
SCHEMBL26419008 0.81 FOLH1 (0.43) FOLH1GLP1RALB
SCHEMBL26427260 0.80 FOLH1 (0.43) FOLH1GLP1RALB
SCHEMBL8122830 0.78 GLP1R (0.53) FOLH1GLP1RALB
SCHEMBL13475019 0.78 GLP1R (0.53) FOLH1GLP1RALB
SCHEMBL26419212 0.78 SIRT5 (0.43) FOLH1GLP1RALB
SCHEMBL12743484 0.76 GLP1R (0.53) FOLH1GLP1RALB
SCHEMBL8121657 0.76 GLP1R (0.51) FOLH1GLP1RALB
SCHEMBL26428067 0.76 FOLH1 (0.40) FOLH1GLP1RALB
SCHEMBL8116094 0.76 GLP1R (0.51) FOLH1GLP1RALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2022098743-A1 COMPOSITIONS, IMAGING, AND THERAPEUTIC METHODS TARGETING FOLATE RECEPTOR 1 (FOLR1) INDI MOLECULAR, INC. (US) 2022-05-12 WO disclosed
WO-2022098745-A1 COMPOSITIONS, DELIVERY SYSTEMS, AND METHODS USEFUL IN TUMOR THERAPY INDI MOLECULAR, INC. (US) 2022-05-12 WO disclosed