SCHEMBL244127

SCHEMBL244127

NC(=O)NN1CCCC1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7749096 0.97 HTT (0.45)
SCHEMBL7749230 0.97 HTT (0.45)
Hydrochloric Acid SCHEMBL27321583 0.97 HTT (0.41)
SCHEMBL7747487 0.97 HTT (0.45)
SCHEMBL1259794 0.97 HTT (0.45)
SCHEMBL15282042 0.97 HTT (0.45)
Hydrochloric Acid SCHEMBL27543811 0.95 HTT (0.44)
Hydrochloric Acid SCHEMBL27317890 0.95 HTT (0.44)
SCHEMBL1259613 0.94
SCHEMBL4778404 0.88 CA2 (0.41)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 273 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-120025515-A Room-temperature self-repairing tough polyurethane elastomer and preparation method and application thereof 中国科学院化学研究所 2025-05-23 CN claimed
US-20250129429-A1 GENE FUSIONS IN SARCOMA FOUNDATION MEDICINE, INC. (US) 2025-04-24 US claimed
EP-4423302-A2 NOVEL KINASE FUSIONS DETECTED BY LIQUID BIOPSY Foundation Medicine, Inc. (US) 2024-09-04 EP claimed
CN-118414439-A Novel kinase fusion by liquid biopsy 基金会医学公司 2024-07-30 CN claimed
EP-4399330-A1 GENE FUSIONS IN SARCOMA Foundation Medicine, Inc. (US) 2024-07-17 EP claimed
WO-2023077104-A2 NOVEL KINASE FUSIONS DETECTED BY LIQUID BIOPSY FOUNDATION MEDICINE, INC. (US) 2023-05-04 WO claimed
WO-2023039539-A1 GENE FUSIONS IN SARCOMA FOUNDATION MEDICINE, INC. (US) 2023-03-16 WO claimed
US-11578372-B2 NTRK1 fusion molecules and uses thereof FOUNDATION MEDICINE, INC. (US) 2023-02-14 US claimed
US-20220243280-A1 NTRK FUSION MOLECULES AND USES THEREOF FOUNDATION MEDICINE, INC. (US) 2022-08-04 US claimed
EP-3980563-A2 NTRK FUSION MOLECULES AND USES THEREOF Foundation Medicine, Inc. (US) 2022-04-13 EP claimed
WO-2020243021-A2 NTRK FUSION MOLECULES AND USES THEREOF FOUNDATION MEDICINE, INC. (US) 2020-12-03 WO claimed
US-20200299775-A1 NOVEL NTRK1 FUSION MOLECULES AND USES THEREOF FOUNDATION MEDICINE, INC. 2020-09-24 US claimed
EP-2914621-A2 NOVEL NTRK1 FUSION MOLECULES AND USES THEREOF Foundation Medicine, Inc. (US) 2015-09-09 EP claimed
US-20150073036-A1 NOVEL NTRK1 FUSION MOLECULES AND USES THEREOF FOUNDATION MEDICINE, INC. 2015-03-12 US claimed
WO-2014071358-A2 NOVEL NTRK1 FUSION MOLECULES AND USES THEREOF FOUNDATION MEDICINE, INC. (US) 2014-05-08 WO claimed
US-6433024-B1 WATER, BENZOYL PEROXIDE, ISOSORBIDE DIESTER, DETERGENT, MOISTURIZER; AND LACTIC, GLYCOLIC, MALIC, OR 2-HYDROXYDECANOIC ACID; SENSITIVE CREAM STIEFEL LABORATORIES, INC. 2002-08-13 US claimed
CN-1327418-A Metallic ink composition for wick type writing instruments DRI MARK PRODUCTS INC (US) 2001-12-19 CN claimed
WO-2001085159-A1 TOPICAL ANTI-ACNE COMPOSITION STIEFEL LABORATORIES, INC. (US) 2001-11-15 WO claimed
CN-118515652-B Crystal form of pyrrolidinyl urea derivative and application thereof 漳州片仔癀药业股份有限公司 2025-11-07 CN disclosed
EP-0083096-A2 Production of urethane compounds Asahi Kasei Kogyo Kabushiki Kaisha (JP) 1983-07-06 EP disclosed