Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | BUB1 | O43683 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.35 |
| ▸ | MAP1LC3B | Q9GZQ8 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7713810 | 0.88 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2ABUB1MAPT | |
| SCHEMBL10001994 | 0.87 | ALDH1A1 (0.48) | ALDH1A1KDM4EKMT2ABUB1MAPT | |
| SCHEMBL24413557 | 0.86 | BUB1 (0.53) | ALDH1A1KDM4EKMT2ABUB1GAA | |
| SCHEMBL10337538 | 0.78 | BUB1 (0.49) | ALDH1A1KDM4EKMT2ABUB1MAPT | |
| SCHEMBL4284354 | 0.78 | ALDH1A1 (0.46) | ALDH1A1KDM4EKMT2ABUB1MAPT | |
| SCHEMBL4281310 | 0.76 | KDM4E (0.44) | ALDH1A1KDM4EKMT2ABUB1MEN1 | |
| SCHEMBL4292313 | 0.74 | ALDH1A1 (0.43) | ALDH1A1KDM4EKMT2ABUB1MAPT | |
| SCHEMBL4236290 | 0.74 | ALDH1A1 (0.47) | ALDH1A1KDM4EKMT2ABUB1MAPT | |
| SCHEMBL4289348 | 0.73 | POLB (0.46) | ALDH1A1KDM4EKMT2ABUB1HPGD | |
| SCHEMBL871448 | 0.73 | ALDH1A1 (0.50) | ALDH1A1KDM4EKMT2AMAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022097115-A1 | AN IMPROVED PROCESS FOR PREPARATION OF PROHEXADIONE AND ITS CALCIUM SALT | HIKAL LIMITED (IN) | 2022-05-12 | — | — | WO | disclosed |