Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 1/20 | 0.42 |
| ▸ | CTSK | P43235 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.42 |
| ▸ | NOTUM | Q6P988 | 3/20 | 0.42 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.41 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.39 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.39 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 2/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | AURKA | O14965 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17297890 | 0.82 | AR (0.61) | CYP11B1CYP11B2ARCTSSCTSK | |
| SCHEMBL19243109 | 0.77 | CYP11B1 (0.50) | CYP11B1CYP11B2CTSSCTSKPDE3B | |
| SCHEMBL10000250 | 0.76 | CCR1 (0.54) | NOTUMHSD17B1HSD17B2KDM1ACCR1 | |
| SCHEMBL5949422 | 0.76 | AR (0.52) | ARCTSSCTSKNOTUMS1PR1 | |
| SCHEMBL4051545 | 0.76 | NOTUM (0.44) | CYP11B1CYP11B2ARPIK3CDNOTUM | |
| SCHEMBL4404647 | 0.74 | CCR1 (0.64) | HSD17B1HSD17B2KDM1ACCR1CCR5 | |
| SCHEMBL5949403 | 0.74 | NOTUM (0.53) | ARCTSSCTSKNOTUMS1PR1 | |
| SCHEMBL30742956 | 0.74 | NOTUM (0.53) | ARCTSSCTSKNOTUMS1PR1 | |
| SCHEMBL30742957 | 0.74 | NOTUM (0.53) | ARCTSSCTSKNOTUMS1PR1 | |
| SCHEMBL21241437 | 0.74 | S1PR1 (0.49) | CYP11B1CYP11B2CTSSCTSKPIK3CD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220144850-A1 | INDOLO HEPTAMYL OXIME ANALOGUE AS PARP INHIBITOR | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220144850-A1 | INDOLO HEPTAMYL OXIME ANALOGUE AS PARP INHIBITOR | PARP1, PARP2, PARP3 | CYP11B1 1616/4885CYP11B2 1388/4885AR 1267/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.