Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1E | P49674 | 16/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 14/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24415104 | 0.83 | NR1H2 (0.39) | — | |
| SCHEMBL24415151 | 0.76 | — | — | |
| SCHEMBL25267501 | 0.72 | CSNK1E (0.36) | CSNK1ECSNK1D | |
| SCHEMBL31319019 | 0.72 | CSNK1E (0.36) | CSNK1ECSNK1D | |
| SCHEMBL24415107 | 0.68 | — | — | |
| SCHEMBL24415148 | 0.65 | — | — | |
| SCHEMBL23099048 | 0.62 | CREBBP (0.46) | CREBBPCYP1A2TDP1 | |
| SCHEMBL14970437 | 0.61 | DPP4 (0.46) | CREBBPCYP1A2TDP1 | |
| SCHEMBL14970436 | 0.61 | DPP4 (0.50) | CREBBPCYP1A2TDP1 | |
| SCHEMBL24415106 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192720-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. | 2023-06-22 | — | — | US | disclosed |
| US-20230192720-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. | 2023-06-22 | — | — | US | disclosed |
| US-20220144854-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230192720-A1 | MACROCYCLIC COMPOUNDS | MCL1, BCL2A1, BCL2L1 | CSNK1E 492/4885CSNK1D 802/4885CREBBP 74/4885 |
| US-20220144854-A1 | MACROCYCLIC COMPOUNDS | MCL1, BCL9, CYC1 | CSNK1E 627/4885CSNK1D 716/4885CREBBP 259/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.