⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24415147 | 0.76 | CSNK1E (0.34) | — | |
| SCHEMBL24415107 | 0.74 | — | — | |
| SCHEMBL14752127 | 0.73 | — | — | |
| SCHEMBL24415104 | 0.71 | NR1H2 (0.39) | — | |
| SCHEMBL24415148 | 0.70 | — | — | |
| SCHEMBL24415106 | 0.66 | — | — | |
| SCHEMBL18195421 | 0.64 | LRRK2 (0.42) | — | |
| SCHEMBL20939651 | 0.62 | KMT2A (0.37) | — | |
| SCHEMBL22421091 | 0.61 | MAP3K14 (0.31) | — | |
| SCHEMBL20939599 | 0.60 | HRH4 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230192720-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. | 2023-06-22 | — | — | US | disclosed |
| US-20230192720-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. | 2023-06-22 | — | — | US | disclosed |
| US-20220144854-A1 | MACROCYCLIC COMPOUNDS | ZENO MANAGEMENT, INC. | 2022-05-12 | — | — | US | disclosed |