Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | OGA | O60502 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | PBRM1 | Q86U86 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 3/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.31 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 2/20 | 0.30 |
| ▸ | MAOB | P27338 | 2/20 | 0.30 |
| ▸ | BACE1 | P56817 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23625404 | 0.90 | ALDH1A1 (0.33) | TDP1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL22423823 | 0.87 | TDP1 (0.49) | TDP1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL22423828 | 0.87 | TDP1 (0.49) | TDP1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL22423829 | 0.87 | TDP1 (0.49) | TDP1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL24499851 | 0.86 | TDP1 (0.39) | TDP1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL13799418 | 0.81 | ALDH1A1 (0.42) | TDP1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL23645657 | 0.79 | TDP1 (0.42) | TDP1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL26038964 | 0.76 | TDP1 (0.39) | TDP1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL8268612 | 0.75 | KCNJ1 (0.39) | TDP1ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL26038963 | 0.75 | TDP1 (0.50) | TDP1ALDH1A1KDM4EGAASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220143042-A1 | FUSED GLYCOSIDASE INHIBITORS | ASCENEURON SA (CH) | 2022-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220143042-A1 | FUSED GLYCOSIDASE INHIBITORS | BACE1, ENGASE, GBA3 | TDP1 534/4885ALDH1A1 628/4885KDM4E 1953/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.