Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.73 |
| ▸ | CYP1A2 | P05177 | 6/20 | 0.70 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.68 |
| ▸ | BLM | P54132 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.61 |
| ▸ | USP2 | O75604 | 5/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.57 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.57 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28869329 | 0.85 | MAPT (1.00) | MAPTCYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL4559572 | 0.82 | SMN1; SMN2 (0.91) | MAPTCYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL8361624 | 0.82 | SMN1; SMN2 (0.97) | MAPTCYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL5195426 | 0.81 | SMN1; SMN2 (1.00) | MAPTCYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL3949148 | 0.80 | MAPT (0.88) | MAPTCYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL3949152 | 0.80 | MAPT (0.88) | MAPTCYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL20236897 | 0.80 | MAPT (0.88) | MAPTCYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL20236181 | 0.78 | MAPT (0.79) | MAPTCYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL5458965 | 0.78 | MAPT (0.79) | MAPTCYP1A2CYP2D6TSHRKMT2A | |
| SCHEMBL13234918 | 0.78 | BLM (1.00) | MAPTTSHRKMT2ASMN1; SMN2BLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022098700-A1 | INHIBITING AN IMMUNE RESPONSE MEDIATED BY ONE OR MORE OF TLR2, RAGE, CCR5, CXCR4 AND CD4 | CASSAVA SCIENCES, INC. (US) | 2022-05-12 | — | — | WO | disclosed |