Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.41 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.41 |
| ▸ | POLRMT | O00411 | 1/20 | 0.39 |
| ▸ | IARS1 | P41252 | 3/20 | 0.39 |
| ▸ | MARS1 | P56192 | 3/20 | 0.38 |
| ▸ | LARS1 | Q9P2J5 | 1/20 | 0.38 |
| ▸ | DOT1L | Q8TEK3 | 2/20 | 0.36 |
| ▸ | GSK3A | P49840 | 1/20 | 0.35 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.35 |
| ▸ | TARS1 | P26639 | 2/20 | 0.34 |
| ▸ | ADK | P55263 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26832023 | 0.87 | POLRMT (0.40) | POLRMTMARS1DOT1LGSK3ARPS6KA3 | |
| SCHEMBL26832290 | 0.87 | POLRMT (0.39) | POLRMTMARS1DOT1LGSK3ARPS6KA3 | |
| SCHEMBL25913394 | 0.85 | POLRMT (0.36) | POLRMTMARS1DOT1LGSK3ARPS6KA3 | |
| SCHEMBL26149119 | 0.85 | POLRMT (0.40) | POLRMTMARS1DOT1LGSK3ARPS6KA3 | |
| SCHEMBL26319911 | 0.84 | POLRMT (0.37) | SLC5A1SLC5A2POLRMTIARS1MARS1 | |
| SCHEMBL26148725 | 0.84 | POLRMT (0.39) | POLRMTMARS1DOT1LGSK3ARPS6KA3 | |
| SCHEMBL26832481 | 0.83 | POLRMT (0.38) | SLC5A1SLC5A2POLRMTIARS1MARS1 | |
| SCHEMBL26832176 | 0.83 | POLRMT (0.39) | SLC5A1SLC5A2POLRMTMARS1DOT1L | |
| SCHEMBL26398893 | 0.83 | POLRMT (0.36) | SLC5A1SLC5A2POLRMTMARS1DOT1L | |
| SCHEMBL26229817 | 0.80 | POLRMT (0.46) | POLRMTDOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022098371-A1 | PRODRUGS OF 1'-SUBSTITUTED CARBA-NUCLEOSIDE ANALOGUES FOR ANTIVIRAL TREATMENT | YAN MATTHEW (US) | 2022-05-12 | — | — | WO | disclosed |