Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 20/20 | 0.56 |
| ▸ | CDK9 | P50750 | 20/20 | 0.56 |
| ▸ | CDK4 | P11802 | 7/20 | 0.56 |
| ▸ | CCND1 | P24385 | 7/20 | 0.56 |
| ▸ | CDK2 | P24941 | 6/20 | 0.56 |
| ▸ | CCNA1 | P78396 | 6/20 | 0.56 |
| ▸ | CDK1 | P06493 | 5/20 | 0.56 |
| ▸ | CCNA2 | P20248 | 5/20 | 0.56 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.56 |
| ▸ | CDK3 | Q00526 | 5/20 | 0.56 |
| ▸ | CDK7 | P50613 | 3/20 | 0.56 |
| ▸ | CCNH | P51946 | 3/20 | 0.56 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.56 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.56 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.56 |
| ▸ | CCNK | O75909 | 1/20 | 0.56 |
| ▸ | CDK14 | O94921 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CCNC | P24863 | 1/20 | 0.56 |
| ▸ | CDK17 | Q00537 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24418932 | 1.00 | CCNT1 (0.56) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL21877666 | 0.85 | CCNT1 (0.65) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL24418930 | 0.85 | CDK9 (0.66) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL24418926 | 0.85 | CDK9 (0.66) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL29558681 | 0.84 | CCNT1 (0.62) | CCNT1CDK9CDK4CCND1CDK2 | |
| Hydrochloric Acid SCHEMBL29558414 | 0.84 | CDK9 (0.65) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL29558482 | 0.82 | CDK9 (0.53) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL29558183 | 0.82 | CCNT1 (0.56) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL24418931 | 0.81 | CDK9 (0.59) | CCNT1CDK9CDK4CCND1CDK2 | |
| SCHEMBL24418845 | 0.81 | CDK9 (0.59) | CCNT1CDK9CDK4CCND1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4240422-A1 | COMPOUNDS AND METHODS FOR MODULATING CDK9 ACTIVITY | Kronos Bio, Inc. (US) | 2023-09-13 | — | — | EP | disclosed |
| WO-2022098843-A1 | COMPOUNDS AND METHODS FOR MODULATING CDK9 ACTIVITY | Kronos Bio, Inc. (US) | 2022-05-12 | — | — | WO | disclosed |
| WO-2022098843-A1 | COMPOUNDS AND METHODS FOR MODULATING CDK9 ACTIVITY | Kronos Bio, Inc. (US) | 2022-05-12 | — | — | WO | disclosed |