Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.70 |
| ▸ | RXRA | P19793 | 10/20 | 0.45 |
| ▸ | RXRB | P28702 | 10/20 | 0.45 |
| ▸ | RXRG | P48443 | 10/20 | 0.45 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GPR142 | Q7Z601 | 1/20 | 0.38 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24409055 | 0.86 | NR1H4 (0.74) | NR1H4RXRARXRBRXRGKDM4E | |
| SCHEMBL24409072 | 0.84 | NR1H4 (0.72) | NR1H4RXRARXRBRXRGHDAC3 | |
| SCHEMBL24419800 | 0.84 | NR1H4 (0.60) | NR1H4RXRARXRBRXRGKDM4E | |
| SCHEMBL24409061 | 0.83 | NR1H4 (0.70) | NR1H4RXRARXRBRXRGFFAR1 | |
| SCHEMBL24419803 | 0.83 | NR1H4 (0.62) | NR1H4RXRARXRBRXRGFFAR1 | |
| SCHEMBL24419766 | 0.83 | NR1H4 (0.50) | NR1H4ALDH1A1GPR142 | |
| SCHEMBL24419674 | 0.83 | NR1H4 (0.59) | NR1H4RXRARXRBRXRGFFAR1 | |
| SCHEMBL24419430 | 0.81 | NR1H4 (0.54) | NR1H4RXRARXRBRXRGFFAR1 | |
| SCHEMBL24419711 | 0.80 | NR1H4 (0.53) | NR1H4RXRARXRBRXRGFFAR1 | |
| SCHEMBL24425232 | 0.80 | NR1H4 (0.62) | NR1H4RXRARXRBRXRGHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022096445-A1 | [(1-PHENYL-5-HETEROARYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-12 | — | — | WO | disclosed |