Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.62 |
| ▸ | RXRA | P19793 | 11/20 | 0.51 |
| ▸ | RXRB | P28702 | 11/20 | 0.51 |
| ▸ | RXRG | P48443 | 11/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GPR52 | Q9Y2T5 | 1/20 | 0.38 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24409072 | 0.87 | NR1H4 (0.72) | NR1H4RXRARXRBRXRGKDM4E | |
| SCHEMBL24419805 | 0.87 | NR1H4 (0.57) | NR1H4RXRARXRBRXRGKDM4E | |
| SCHEMBL24409020 | 0.85 | NR1H4 (0.46) | NR1H4RXRARXRBRXRGHSD17B10 | |
| SCHEMBL24409133 | 0.83 | NR1H4 (0.44) | NR1H4RXRARXRBRXRGKDM4E | |
| SCHEMBL24419674 | 0.80 | NR1H4 (0.59) | NR1H4RXRARXRBRXRGKDM4E | |
| SCHEMBL24409055 | 0.80 | NR1H4 (0.74) | NR1H4RXRARXRBRXRGKDM4E | |
| SCHEMBL24419672 | 0.80 | NR1H4 (0.70) | NR1H4RXRARXRBRXRGKDM4E | |
| SCHEMBL24419803 | 0.80 | NR1H4 (0.62) | NR1H4RXRARXRBRXRGKDM4E | |
| SCHEMBL24409061 | 0.78 | NR1H4 (0.70) | NR1H4RXRARXRBRXRGKDM4E | |
| SCHEMBL24409202 | 0.78 | NR1H4 (0.56) | NR1H4RXRARXRBRXRGHDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022096448-A1 | [(5-PHENYL-5-HETEROARYL-1H-PYRAZOL-3-YL)OXY] ACETIC ACID DERIVATIVES AS SAFENERS FOR THE PROTECTION OF USEFUL PLANTS AND CROP PLANTS | BAYER AKTIENGESELLSCHAFT (DE) | 2022-05-12 | — | — | WO | disclosed |