Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | HTR1A | P08908 | 1/20 | 0.36 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.36 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.36 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.36 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.36 |
| ▸ | CHRNA10 | Q9GZZ6 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10530238 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL10530231 | 0.83 | ALDH1A1 (0.53) | ALDH1A1LMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL1715036 | 0.78 | — | — | |
| SCHEMBL11694940 | 0.78 | ALDH1A1 (0.48) | ALDH1A1LMNAHSD17B10TSHRALOX15 | |
| SCHEMBL28773802 | 0.77 | MGAM (0.46) | ALDH1A1LMNATSHRALOX15GAA | |
| Hydrochloric Acid SCHEMBL9760071 | 0.76 | — | — | |
| Bromide SCHEMBL11871852 | 0.76 | — | — | |
| SCHEMBL11788854 | 0.74 | ALDH1A1 (0.50) | ALDH1A1LMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL14415262 | 0.74 | ALDH1A1 (0.43) | ALDH1A1LMNAHSD17B10TSHRSMN1; SMN2 | |
| SCHEMBL6618960 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099060-A2 | BICYCLIC PYRIDAZINONES AND METHODS OF USE THEREOF | ALIGOS THERAPEUTICS, INC. (US) | 2022-05-12 | — | — | WO | disclosed |