Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Butyric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.52 |
| ▸ | FFAR3 | O14843 | 3/20 | 0.87 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.87 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.87 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.87 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.87 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | SLC15A2 | Q16348 | 1/20 | 0.53 |
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.52 |
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARD | Q03181 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 7/20 | 0.52 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.52 |
| ▸ | TSHR | P16473 | 4/20 | 0.52 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | TLR2 | O60603 | 2/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | FABP4 | P15090 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butyric Acid SCHEMBL3479926 | 1.00 | FFAR3 (0.87) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL8013978 | 1.00 | FFAR3 (0.87) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL9224594 | 1.00 | FFAR3 (0.87) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL8856251 | 1.00 | FFAR3 (0.87) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL385002 | 1.00 | FFAR3 (0.87) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL11852319 | 1.00 | FFAR3 (0.87) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL9115265 | 1.00 | FFAR3 (0.87) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL9215318 | 1.00 | FFAR3 (0.87) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL9551882 | 1.00 | FFAR3 (0.87) | FFAR3HDAC3HDAC1HDAC2HDAC8 | |
| Butyric Acid SCHEMBL10577104 | 1.00 | FFAR3 (0.87) | FFAR3HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 106938 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12046756-B2 | Cellulose derivative composition for secondary battery binder and method of preparing composition for secondary battery electrode comprising the same | ELECTRONICS AND TELECOMMUNICATIONS RESEARCH INSTITUTE (KR) | 2024-07-23 | — | — | US | claimed |
| CN-118368994-A | Aerosol-generating material comprising chitosan and other binders | 尼科创业贸易有限公司 | 2024-07-19 | — | — | CN | claimed |
| WO-2024149292-A1 | BLOOD VESSEL CLOSING ADHESIVE, PREPARATION METHOD THEREFOR AND USE THEREOF | 苏州美创医疗科技有限公司 | 2024-07-18 | — | — | WO | claimed |
| EP-3925601-B1 | GASTRO-RESISTANT FORMULATION CONTAINING POSACONAZOLE AND A POLYMERIC PRECIPITATION INHIBITOR | TIEFENBACHER ALFRED E GMBH & CO KG (DE) | 2024-07-17 | — | — | EP | claimed |
| EP-4400552-A1 | ACTIVE ENERGY RAY-CURABLE INKJET INK AND IMAGE RECORDING METHOD | FUJIFILM Corporation (JP) | 2024-07-17 | — | — | EP | claimed |
| EP-4400166-A2 | METHODS FOR IMPLANTING AND REVERSING STIMULI-RESPONSIVE IMPLANTS | Contraline, Inc. (US) | 2024-07-17 | — | — | EP | claimed |
| CN-118340735-A | Propiverine hydrochloride osmotic pump controlled release tablet and preparation method thereof | 九华华源药业(桂林)有限公司 | 2024-07-16 | — | — | CN | claimed |
| CN-118165627-B | High-performance high-safety paint and preparation method thereof | 江苏扬瑞新型材料股份有限公司 | 2024-07-16 | — | — | CN | claimed |
| US-12040451-B2 | Stack-type electrode assembly comprising electrode with insulation layer and lithium secondary battery comprising the same | LG ENERGY SOLUTION, LTD. (KR) | 2024-07-16 | — | — | US | claimed |
| CN-118340734-A | Erdosteine solid dispersible tablet, and preparation method and application thereof | 九华华源药业(桂林)有限公司 | 2024-07-16 | — | — | CN | claimed |
| US-3950284-A | VINYL POLYMERS, GRAFT OR BLOCK POLYMERS | TORAY INDUSTRIES, INC. (JA) | 1976-04-13 | — | — | US | claimed |
| US-3948674-A | AN ACRYLIC HOMO- OR CO-POLYMER | MONSANTO COMPANY (US) | 1976-04-06 | — | — | US | claimed |
| US-3943063-A | Preparation of microcapsules | TOYO JOZO COMPANY, LTD. (JA) | 1976-03-09 | — | — | US | claimed |
| US-3941596-A | Thermographic processes using polymer layer capable of existing in metastable state | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-03-02 | — | — | US | claimed |
| US-3938515-A | Novel drug permeable wall | ALZA CORPORATION (US) | 1976-02-17 | — | — | US | claimed |
| US-3937508-A | Vehicle body and bumper assembly | FORD MOTOR COMPANY (US) | 1976-02-10 | — | — | US | claimed |
| US-3935334-A | Process for preparing a metallized resin film for condenser element | OIKE & COMPANY, LTD. (JA) | 1976-01-27 | — | — | US | claimed |
| US-3933508-A | ORGANIC SILVER SALT, SILVER HALIDE, REDUCING AGENT, BINDER | FUJI PHOTO FILM CO., LTD. (JA) | 1976-01-20 | — | — | US | claimed |
| US-3932250-A | Method for manufacturing metal foil- or plastic film-overlaid laminate | MITSUBISHI GAS CHEMICAL CO., LTD. (JA) | 1976-01-13 | — | — | US | claimed |
| US-3932191-A | WATER AND POLYCARBOXYLIC ACID RESINS | PPG INDUSTRIES, INC. (US) | 1976-01-13 | — | — | US | claimed |