Butyric Acid

Butyric Acid

SCHEMBL385002

CC(=O)O.CCCC(=O)O.CCCC(=O)O.CCCC(=O)O

nearest known ligand 0.87

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of Butyric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 known ✓ P03372 1/20 0.52
FFAR3 O14843 3/20 0.87
HDAC3 O15379 1/20 0.87
HDAC1 Q13547 1/20 0.87
HDAC2 Q92769 1/20 0.87
HDAC8 Q9BY41 1/20 0.87
AKR1B1 P15121 1/20 0.55
LMNA P02545 2/20 0.53
SLC15A2 Q16348 1/20 0.53
GPR84 Q9NQS5 7/20 0.52
PPARG P37231 7/20 0.52
PPARD Q03181 7/20 0.52
PPARA Q07869 7/20 0.52
HDAC11 Q96DB2 5/20 0.52
TSHR P16473 4/20 0.52
PTPN1 P18031 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Butyric Acid SCHEMBL24420 1.00 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL3479926 1.00 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL8013978 1.00 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL9224594 1.00 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL8856251 1.00 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL11852319 1.00 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL9115265 1.00 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL9215318 1.00 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL9551882 1.00 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8
Butyric Acid SCHEMBL10577104 1.00 FFAR3 (0.87) FFAR3HDAC3HDAC1HDAC2HDAC8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021054654-A1 QUANTUM DOT-POLYMER COMPOSITE PARTICLES AND METHOD FOR PREPARING SAME 주식회사 한솔케미칼 2021-03-25 WO disclosed
EP-3006499-B1 CLARIFYING AGENT COMPOSITION, AND POLYOLEFIN RESIN COMPOSITION CONTAINING SAME ADEKA CORP (JP) 2019-10-09 EP disclosed
US-9701812-B2 Clarifying agent composition, and polyolefin resin composition containing same ADEKA CORPORATION (JP) 2017-07-11 US disclosed
US-20160115295-A1 CLARIFYING AGENT COMPOSITION, AND POLYOLEFIN RESIN COMPOSITION CONTAINING SAME ADEKA CORPORATION (JP) 2016-04-28 US disclosed
EP-3006499-A1 CLARIFYING AGENT COMPOSITION, AND POLYOLEFIN RESIN COMPOSITION CONTAINING SAME Adeka Corporation (JP) 2016-04-13 EP disclosed
US-8470223-B2 Thermoplastic resin film and method for manufacturing the same FUJIFILM CORPORATION (JP) 2013-06-25 US disclosed
US-8247041-B2 Cellulose acylate film FUJIFILM CORPORATION (JP) 2012-08-21 US disclosed
US-8221845-B2 Cellulose resin film and method for producing the same FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
US-8221896-B2 Cellulose resin film and method for producing the same FUJIFILM CORPORATION (JP) 2012-07-17 US disclosed
US-8197726-B2 Cellulose acylate film and method for producing same FUJIFILM CORPORATION (JP) 2012-06-12 US disclosed
WO-2006132402-A1 METHOD FOR PRODUCING CELLULOSE ACYLATE RESIN FILM FUJIFILM CORPORATION (JP) 2006-12-14 WO disclosed
WO-2006129685-A1 METHOD FOR PRODUCING THERMOPLASTIC FILM FUJIFILM CORPORATION (JP) 2006-12-07 WO disclosed
WO-2006129824-A1 METHOD AND APPARATUS FOR PRODUCING CELLULOSE ACYLATE FILM, AND CELLULOSE ACYLATE FILM FUJIFILM CORPORATION (JP) 2006-12-07 WO disclosed
WO-2006129822-A1 METHOD FOR PRODUCING THERMOPLASTIC FILM AND OPTICAL COMPENSATION FILM FOR LIQUID CRYSTAL DISPLAY PANELS PRODUCED BY USING THE METHOD FUJIFILM CORPORATION (JP) 2006-12-07 WO disclosed
WO-2006129825-A1 METHOD FOR PRODUCING CELLULOSE ACYLATE FILM AND OPTICAL COMPENSATION FILM FOR LIQUID CRYSTAL DISPLAY PLATE PRODUCED BY USING THE METHOD FUJIFILM CORPORATION (JP) 2006-12-07 WO disclosed
WO-2006126717-A1 METHOD FOR PRODUCING THERMOPLASTIC FILM FUJIFILM CORPORATION (JP) 2006-11-30 WO disclosed
US-20060066011-A1 Cellulose acylate film and process for producing the same, and optical film and image display device using the cellulose acylate film FUJI PHOTO FILM CO., LTD. 2006-03-30 US disclosed
WO-2006013869-A1 THERMOPLASTIC FILM AND METHOD OF PRODUCING THE SAME FUJIFILM CORPORATION (JP) 2006-02-09 WO disclosed
EP-0587106-B1 Compositions containing lipophilic salts having neutron activable cations VECTORPHARMA INT (IT) 1997-07-30 EP disclosed
EP-0587106-A2 Lipophilic salts containing neutron activable isotopes and compositions containing them VECTORPHARMA INTERNATIONAL S.p.A. (IT) 1994-03-16 EP disclosed