Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 3/20 | 0.65 |
| ▸ | LMNA | P02545 | 2/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.65 |
| ▸ | TK2 | O00142 | 1/20 | 0.63 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.61 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.59 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.59 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27054137 | 1.00 | TK1 (0.65) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL25824058 | 0.91 | TK1 (0.54) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL9780661 | 0.87 | TK1 (0.69) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL9780646 | 0.87 | TK1 (0.69) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL21071421 | 0.87 | TK1 (0.65) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL21115872 | 0.87 | TK1 (0.65) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL21115874 | 0.87 | TK1 (0.65) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL22560281 | 0.87 | TK1 (0.65) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL5982320 | 0.87 | TK1 (0.65) | TK1LMNASMN1; SMN2TK2ALOX12 | |
| SCHEMBL5982324 | 0.87 | TK1 (0.65) | TK1LMNASMN1; SMN2TK2ALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2023220428-A1 | COMPOSITIONS FOR EDITING ASS1 TRANSCRIPTS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |