Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.66 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.66 |
| ▸ | HSPA5 | P11021 | 2/20 | 0.54 |
| ▸ | HSPA8 | P11142 | 2/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | TP53 | P04637 | 2/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | PNP | P00491 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.50 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | GAPDH | P04406 | 2/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.47 |
| ▸ | HBB | P68871 | 1/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 2/20 | 0.46 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.46 |
| ▸ | FPR2 | P25090 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13835070 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL30274706 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL6302264 | 1.00 | ADORA3 (0.66) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL658005 | 0.89 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL5982465 | 0.89 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL658006 | 0.89 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL5982454 | 0.89 | ADORA3 (0.67) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL18952838 | 0.88 | ADORA3 (0.66) | ADORA3ADORA2AHSPA5HSPA8RXFP1 | |
| SCHEMBL31685786 | 0.88 | ADORA3 (0.52) | ADORA3ADORA2ARXFP1LMNATP53 | |
| SCHEMBL5983124 | 0.88 | ADORA3 (0.52) | ADORA3ADORA2ARXFP1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240026358-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2024-01-25 | — | — | US | disclosed |
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |