Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 3/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | EP300 | Q09472 | 11/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.34 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.34 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24420605 | 0.90 | FGFR1 (0.39) | FGFR1SLC22A6EP300MAPTCYP2D6 | |
| SCHEMBL21690880 | 0.84 | FGFR1 (0.39) | FGFR1SLC22A6EP300MAPTCYP2D6 | |
| SCHEMBL23546239 | 0.83 | FGFR1 (0.40) | FGFR1SLC22A6EP300MAPTCYP2D6 | |
| SCHEMBL2967556 | 0.81 | FGFR1 (0.43) | FGFR1SLC22A6EP300MAPT | |
| SCHEMBL23343373 | 0.80 | FGFR1 (0.44) | FGFR1SLC22A6EP300MAPTCYP2D6 | |
| SCHEMBL6379845 | 0.79 | FGFR1 (0.43) | FGFR1SLC22A6EP300MAPTCYP2D6 | |
| SCHEMBL19631097 | 0.78 | FGFR1 (0.45) | FGFR1SLC22A6EP300HTTLMNA | |
| SCHEMBL22078831 | 0.77 | FGFR1 (0.43) | FGFR1SLC22A6EP300MAPTCYP2D6 | |
| SCHEMBL3680116 | 0.77 | FGFR1 (0.52) | FGFR1SLC22A6EP300MAPTCYP2D6 | |
| SCHEMBL1765906 | 0.77 | FGFR1 (0.43) | FGFR1SLC22A6EP300MAPTCYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |