SCHEMBL19631097

SCHEMBL19631097

CCCCn1ccc(N)nc1=O

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FGFR1 P11362 6/20 0.45
EP300 Q09472 7/20 0.42
TLR8 Q9NR97 3/20 0.41
SLC22A6 Q4U2R8 1/20 0.40
ALDH1A1 P00352 1/20 0.40
POLB P06746 1/20 0.40
KMT2A Q03164 1/20 0.40
HRH4 Q9H3N8 1/20 0.39
LMNA P02545 1/20 0.39
TSHR P16473 1/20 0.39
HTT P42858 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13261399 0.95 TLR8 (0.47) FGFR1EP300TLR8
SCHEMBL25628523 0.93 FGFR1 (0.48) FGFR1EP300TLR8
SCHEMBL4245808 0.93 FGFR1 (0.48) FGFR1EP300TLR8
SCHEMBL13975422 0.93 FGFR1 (0.48) FGFR1EP300TLR8
SCHEMBL27723178 0.93 FGFR1 (0.48) FGFR1EP300TLR8
SCHEMBL27977634 0.93 FGFR1 (0.48) FGFR1EP300TLR8
SCHEMBL2967556 0.89 FGFR1 (0.43) FGFR1EP300SLC22A6
SCHEMBL23343373 0.89 FGFR1 (0.44) FGFR1EP300SLC22A6LMNA
SCHEMBL1532184 0.84 FGFR1 (0.42) FGFR1EP300SLC22A6LMNA
SCHEMBL20012082 0.83 FGFR1 (0.41) FGFR1EP300SLC22A6LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11667667-B2 Steroid derivative FXR agonist CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2023-06-06 US disclosed
US-20230023797-A1 MAJORITY LOGIC GATE WITH INPUT PARAELECTRIC CAPACITORS Kepler Computing Inc. (US) 2023-01-26 US disclosed
WO-2022132194-A2 OLIGONUCLEOTIDE ANALOGUE THERAPEUTICS FOR TREATMENT OF NEUROMUSCULAR DISEASE NEUBASE THERAPEUTICS, INC. (US) 2022-06-23 WO disclosed
WO-2022099159-A1 OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF WAVE LIFE SCIENCES LTD. (SG) 2022-05-12 WO disclosed
US-20210322923-A1 SYSTEM AND PROCESS OF CAPTURING CARBON DIOXIDE FROM FLUE GASES CARBON CLEAN SOLUTIONS LIMITED (GB) 2021-10-21 US disclosed
US-11141694-B2 System and process of capturing carbon dioxide from flue gases CARBON CLEAN SOLUTIONS LIMITED (GB) 2021-10-12 US disclosed
US-20210040140-A1 Steroid Derivative FXR Agonist CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) 2021-02-11 US disclosed
US-10738718-B2 Bi-fuel engine with increased power ALSET IP S A R.L. (LU) 2020-08-11 US disclosed
EP-1836285-B1 INTEGRATED ALKYLATION PROCESS USING IONIC LIQUID CATALYSTS CHEVRON USA INC (US) 2019-11-20 EP disclosed
WO-2017201325-A1 COMBINATIONS OF MRNAS ENCODING IMMUNE MODULATING POLYPEPTIDES AND USES THEREOF MODERNATX, INC. (US) 2017-11-23 WO disclosed
CN-104003945-A Synthetic method of pyrimidine type chiral surface active agents UNIV YANGZHOU 2014-08-27 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11667667-B2 Steroid derivative FXR agonist NR1H4, SLC10A1, FXR1 FGFR1 83/4885EP300 4318/4885TLR8 299/4885
US-20210040140-A1 Steroid Derivative FXR Agonist NR1H4, SLC10A1, FXR1 FGFR1 83/4885EP300 4318/4885TLR8 299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.