Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPRT1 | P00492 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | PNP | P00491 | 4/20 | 0.34 |
| ▸ | BRD4 | O60885 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | GDA | Q9Y2T3 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18545322 | 0.77 | GDA (0.43) | BRD4MEN1BLMKMT2AGDA | |
| SCHEMBL19464429 | 0.70 | ALDH1A1 (0.39) | HPRT1ALDH1A1BRD4HPGD | |
| SCHEMBL2982031 | 0.69 | HPRT1 (0.53) | HPRT1ALDH1A1PNPBLMKMT2A | |
| SCHEMBL23240695 | 0.68 | ADORA2A (0.33) | ALDH1A1 | |
| SCHEMBL18545316 | 0.67 | GDA (0.43) | BRD4MEN1BLMKMT2AGDA | |
| SCHEMBL21383159 | 0.66 | HPRT1 (0.48) | HPRT1ALDH1A1ACVR1HPGD | |
| SCHEMBL20182463 | 0.64 | TNKS2 (0.32) | — | |
| SCHEMBL19472376 | 0.64 | MEN1 (0.36) | ALDH1A1BRD4MEN1BLMKMT2A | |
| SCHEMBL19035767 | 0.63 | GDA (0.30) | GDA | |
| SCHEMBL21451309 | 0.63 | ALDH1A1 (0.36) | HPRT1ALDH1A1BLMHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |