Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 4/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.37 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.35 |
| ▸ | FFAR1 | O14842 | 8/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 2/20 | 0.34 |
| ▸ | REN | P00797 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24423338 | 1.00 | MGLL (0.39) | MGLLFFAR4TBK1HCRTR2FFAR1 | |
| SCHEMBL24423081 | 1.00 | MGLL (0.39) | MGLLFFAR4TBK1HCRTR2FFAR1 | |
| SCHEMBL29585204 | 1.00 | MGLL (0.39) | MGLLFFAR4TBK1HCRTR2FFAR1 | |
| SCHEMBL24423965 | 1.00 | MGLL (0.39) | MGLLFFAR4TBK1HCRTR2FFAR1 | |
| SCHEMBL24423068 | 1.00 | MGLL (0.39) | MGLLFFAR4TBK1HCRTR2FFAR1 | |
| SCHEMBL29584172 | 0.88 | FFAR4 (0.36) | FFAR4TBK1HCRTR2FFAR1CYP3A4 | |
| SCHEMBL29243425 | 0.88 | FFAR4 (0.36) | FFAR4TBK1HCRTR2FFAR1CYP3A4 | |
| SCHEMBL24424175 | 0.88 | FFAR4 (0.36) | FFAR4TBK1HCRTR2FFAR1CYP3A4 | |
| SCHEMBL24423714 | 0.88 | MGLL (0.33) | MGLLRENCYP3A4 | |
| SCHEMBL24423448 | 0.88 | MGLL (0.33) | MGLLRENCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |