Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.45 |
| ▸ | CA2 | P00918 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 2/20 | 0.41 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.40 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.40 |
| ▸ | RELA | Q04206 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27063727 | 1.00 | BTK (0.52) | BTKGAAEPHX1CA1CA2 | |
| SCHEMBL27419729 | 1.00 | BTK (0.52) | BTKGAAEPHX1CA1CA2 | |
| SCHEMBL509416 | 0.94 | BTK (0.50) | BTKGAAEPHX1CA1CA2 | |
| Water SCHEMBL17140922 | 0.92 | CTSK (0.49) | BTKGAAEPHX1CA1CA2 | |
| SCHEMBL16520179 | 0.89 | BTK (0.54) | BTKGAAEPHX1CA1CA2 | |
| SCHEMBL15542249 | 0.89 | BTK (0.54) | BTKGAAEPHX1CA1CA2 | |
| SCHEMBL16653735 | 0.89 | BTK (0.54) | BTKGAAEPHX1CA1CA2 | |
| SCHEMBL8220153 | 0.83 | BTK (0.54) | BTKGAAEPHX1CA1CA2 | |
| Formaldehyde SCHEMBL28082188 | 0.82 | BTK (0.68) | BTKGAAEPHX1CA1CA2 | |
| SCHEMBL369297 | 0.82 | BTK (0.72) | BTKGAAEPHX1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |