Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GSK3B | P49841 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | WNT1 | P04628 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RET | P07949 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24424717 | 0.81 | CHRNA7 (0.51) | ALDH1A1KDM4EHPGDALOX15LMNA | |
| SCHEMBL25090838 | 0.78 | MAPT (0.60) | ALDH1A1KDM4EHPGDALOX15LMNA | |
| SCHEMBL24424710 | 0.77 | ACACB (0.43) | ALDH1A1HPGDGSK3BEPHX2TP53 | |
| SCHEMBL24424092 | 0.77 | KDM4E (0.47) | ALDH1A1KDM4EHPGDALOX15LMNA | |
| SCHEMBL24424559 | 0.76 | KDM4E (0.52) | ALDH1A1KDM4EHPGDALOX15LMNA | |
| SCHEMBL12993901 | 0.76 | ALDH1A1 (0.67) | ALDH1A1LMNAMEN1KMT2ATP53 | |
| SCHEMBL29929246 | 0.76 | TLR9 (0.66) | — | |
| SCHEMBL22463511 | 0.76 | TLR9 (0.66) | — | |
| SCHEMBL23707380 | 0.75 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDALOX15LMNA | |
| SCHEMBL13061265 | 0.75 | ALDH1A1 (0.62) | ALDH1A1KDM4EKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |