Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 6/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 6/20 | 0.44 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | CHRNB4 | P30926 | 4/20 | 0.40 |
| ▸ | CHRNA3 | P32297 | 4/20 | 0.40 |
| ▸ | CACNA2D1 | P54289 | 2/20 | 0.39 |
| ▸ | CACNA2D2 | Q9NY47 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.39 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24746250 | 0.94 | SLC6A9 (0.41) | CHRNB2CHRNA4SLC6A9MAPTCHRNB4 | |
| SCHEMBL17664587 | 0.91 | MAPT (0.49) | CHRNB2CHRNA4SLC6A9MAPTCHRNB4 | |
| SCHEMBL24746030 | 0.84 | KHK (0.48) | CHRNB2CHRNA4SLC6A9CACNA2D1CACNA2D2 | |
| SCHEMBL2687453 | 0.84 | KHK (0.48) | CHRNB2CHRNA4SLC6A9CACNA2D1CACNA2D2 | |
| SCHEMBL14318799 | 0.84 | KHK (0.48) | CHRNB2CHRNA4SLC6A9CACNA2D1CACNA2D2 | |
| SCHEMBL31182213 | 0.83 | MAP4K4 (0.43) | CHRNB2CHRNA4SLC6A9CHRNB4CHRNA3 | |
| SCHEMBL23107561 | 0.82 | SLC6A9 (0.42) | CHRNB2CHRNA4SLC6A9MAPTCHRNB4 | |
| SCHEMBL23107560 | 0.82 | SLC6A9 (0.42) | CHRNB2CHRNA4SLC6A9MAPTCHRNB4 | |
| SCHEMBL23133785 | 0.82 | SLC6A9 (0.42) | CHRNB2CHRNA4SLC6A9MAPTCHRNB4 | |
| SCHEMBL23515067 | 0.82 | MAPT (0.49) | CHRNB2CHRNA4SLC6A9MAPTCHRNB4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099144-A1 | ΡΡΑRγ MODULATORS AND METHODS OF USE | Eisai R&D Mangement Co., Ltd. (JP) | 2022-05-12 | — | — | WO | disclosed |