SCHEMBL24425916

SCHEMBL24425916

c1nc2ccc(-c3ccc4ncoc4c3)cc2o1

nearest known ligand 0.72

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DYRK1A Q13627 3/20 0.72
NPC1 O15118 3/20 0.45
RAB9A P51151 3/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
PIK3CA P42336 1/20 0.44
MTOR P42345 1/20 0.44
LMNA P02545 1/20 0.42
FFAR1 O14842 1/20 0.40
PPARD Q03181 1/20 0.40
TAS1R3 Q7RTX0 1/20 0.40
TAS1R1 Q7RTX1 1/20 0.40
NAMPT P43490 1/20 0.39
PDE4A P27815 2/20 0.39
PDE4B Q07343 2/20 0.39
PDE4C Q08493 2/20 0.39
PDE4D Q08499 2/20 0.39
PRMT5 O14744 1/20 0.38
WDR77 Q9BQA1 1/20 0.38
CHRNB2 P17787 1/20 0.38
CHRNA4 P43681 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29689417 0.90 DYRK1A (0.62) DYRK1ANPC1RAB9ASMN1; SMN2PIK3CA
SCHEMBL28172473 0.88 DYRK1A (0.60) DYRK1ANPC1RAB9ASMN1; SMN2PIK3CA
SCHEMBL24156066 0.88 DYRK1A (0.60) DYRK1ANPC1RAB9ASMN1; SMN2PIK3CA
SCHEMBL27285079 0.87 DYRK1A (0.58) DYRK1ANPC1RAB9ASMN1; SMN2PIK3CA
SCHEMBL17231481 0.85 DYRK1A (0.57) DYRK1ANPC1RAB9ASMN1; SMN2PIK3CA
SCHEMBL2458438 0.84 DYRK1A (0.55) DYRK1ANPC1RAB9ASMN1; SMN2PIK3CA
SCHEMBL24155550 0.84 DYRK1A (0.55) DYRK1APIK3CAMTORFFAR1PPARD
SCHEMBL17231524 0.84 DYRK1A (0.55) DYRK1ANPC1RAB9ASMN1; SMN2PIK3CA
SCHEMBL2461206 0.82 DYRK1A (0.54) DYRK1APIK3CAMTORKLK3
SCHEMBL17691904 0.82 DYRK1A (0.58) DYRK1ANPC1RAB9ASMN1; SMN2PIK3CA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11333976-B2 Resin, photosensitive resin composition, electronic component and display device using the same TORAY INDUSTRIES, INC. (JP) 2022-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11333976-B2 Resin, photosensitive resin composition, electronic component and display device using the same EED, RPL19, RARA DYRK1A 2843/4885NPC1 4393/4885RAB9A 716/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.