Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 17/20 | 0.42 |
| ▸ | LCK | P06239 | 1/20 | 0.39 |
| ▸ | AURKA | O14965 | 1/20 | 0.33 |
| ▸ | FGR | P09769 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | SRC | P12931 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19876242 | 0.78 | BTK (0.55) | BTKLCK | |
| SCHEMBL17645641 | 0.72 | BTK (0.60) | BTKLCK | |
| SCHEMBL27462708 | 0.68 | BTK (0.64) | BTKLCK | |
| SCHEMBL19878118 | 0.63 | BTK (0.38) | BTKLCKPOLBKMT2ASMN1; SMN2 | |
| SCHEMBL27457768 | 0.63 | BTK (0.54) | BTKLCKKMT2A | |
| SCHEMBL30950500 | 0.63 | BTK (0.67) | BTKLCK | |
| SCHEMBL17645776 | 0.63 | BTK (0.67) | BTKLCK | |
| SCHEMBL30950558 | 0.63 | BTK (0.54) | BTKLCKKMT2A | |
| SCHEMBL19876263 | 0.62 | BTK (0.60) | BTKLCK | |
| SCHEMBL30950479 | 0.62 | BTK (0.53) | BTKLCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3500569-B1 | 2-OXO-IMIDAZOPYRIDINES AS REVERSIBLE BTK INHIBITORS AND USES THEREOF | MERCK PATENT GMBH (DE) | 2022-05-18 | — | — | EP | disclosed |