Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 18/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | RORC | P51449 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24426975 | 0.95 | BDKRB2 (0.55) | BDKRB2CYP3A4 | |
| SCHEMBL21030187 | 0.94 | BDKRB2 (0.54) | BDKRB2CYP3A4RORC | |
| SCHEMBL24427017 | 0.92 | BDKRB2 (0.56) | BDKRB2CYP3A4 | |
| SCHEMBL21030554 | 0.89 | BDKRB2 (0.54) | BDKRB2CYP3A4 | |
| SCHEMBL22334211 | 0.88 | BDKRB2 (0.58) | BDKRB2CYP3A4RORC | |
| SCHEMBL24180708 | 0.87 | BDKRB2 (0.52) | BDKRB2CYP3A4 | |
| SCHEMBL22320137 | 0.86 | BDKRB2 (0.53) | BDKRB2CYP3A4 | |
| SCHEMBL22320134 | 0.86 | BDKRB2 (0.53) | BDKRB2CYP3A4 | |
| Crictibant SCHEMBL21001160 | 0.86 | BDKRB2 (0.56) | BDKRB2CYP3A4 | |
| Deucrictibant SCHEMBL21001161 | 0.86 | BDKRB2 (0.56) | BDKRB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998259-A1 | NOVEL BRADYKININ B2 RECEPTOR ANTAGONISTS | Pharvaris Netherlands B.V. (NL) | 2022-05-18 | — | — | EP | disclosed |