Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB2 | P30411 | 20/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21030338 | 0.93 | BDKRB2 (0.58) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL24426955 | 0.91 | BDKRB2 (0.58) | BDKRB2 | |
| SCHEMBL24427026 | 0.88 | BDKRB2 (0.61) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL24427022 | 0.87 | BDKRB2 (0.63) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL24427027 | 0.87 | BDKRB2 (0.63) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL22334172 | 0.84 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL24427021 | 0.84 | BDKRB2 (0.57) | BDKRB2 | |
| SCHEMBL24427029 | 0.83 | BDKRB2 (0.45) | BDKRB2 | |
| SCHEMBL21030336 | 0.81 | BDKRB2 (0.59) | BDKRB2CYP3A4CYP2C19 | |
| SCHEMBL13145429 | 0.81 | BDKRB2 (0.78) | BDKRB2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3998259-A1 | NOVEL BRADYKININ B2 RECEPTOR ANTAGONISTS | Pharvaris Netherlands B.V. (NL) | 2022-05-18 | — | — | EP | disclosed |